Section snippets Definition and epidemiology DDHN is usually defined as a de-novo haematological malignancy originating from transplanted donor haematopoietic stem cells and is unrelated to the original recipient's neoplasm.2, 12 DDHN most often manifests as a myeloid disease (eg, AML, myelodysplastic syndrome, myeloproliferative neoplasm, or myelodysplastic syndrome/myeloproliferative neoplasm) but lymphoid neoplasms can also occur.13, 14 Heterogeneity in definition, detection methods, and...