Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile
Articles by Amanda Suttle
A Beginner's Guide To CHO Culture: Bioprocess Modes – Batch, Fed-Batch, And Perfusion
By Amanda Suttle and Ma Sha, Eppendorf Inc. Recombinant protein manufacturing in Chinese Hamster Ovary (CHO) cells represents more than 70 % of the entire biopharmaceutical industry. Specifically, human monoclonal antibodies (hmAbs) in CHO cells play a major role in the therapeutic markets and have for decades.
A Beginner's Guide To CHO Culture: Bioprocess Modes – Batch, Fed-Batch, And Perfusion
By Amanda Suttle and Ma Sha, Eppendorf Inc. Recombinant protein manufacturing in Chinese Hamster Ovary (CHO) cells represents more than 70 % of the entire biopharmaceutical industry. Specifically, human monoclonal antibodies (hmAbs) in CHO cells play a major role in the therapeutic markets and have for decades.
How Scale Up Assist Using the BioFlo® 720 Bioreactor Control System Can Help Your Antibody Production Workflow
By Amanda Suttle, John Longsworth, and Ma Sha, Eppendorf, Inc., To scale upstream bioprocesses, an effective scale-up strategy is required to ensure the reproducibility of both cell culture growth and batch yields at large working volumes, ideally with little or no additional optimization. The Constant Power approach is a successful method for matching bioreactor yields at different scales.
Improving Antibody Production Workflow Using The BioFlo 720 Bioreactor Control System
By Amanda Suttle, John Longsworth, and Ma Sha, Eppendorf, Inc., To scale upstream bioprocesses, an effective scale-up strategy is required to ensure the reproducibility of both cell culture growth and batch yields at large working volumes, ideally with little or no additional optimization. The Constant Power approach is a successful method for matching bioreactor yields at different scales.
Parallel Fed-batch CHO Culture On SciVario Twin
By Amanda Suttle and Ma Sha, Eppendorf, Inc., We performed fed-batch cultures using BioBLU® 1c and 3c Single-Use Vessels controlled in parallel by the new SciVario® twin bioreactor control system. This method highlights the SciVario twin’s capabilities to run complex processes simultaneously using various sized vessels. The initial release of SciVario twin can control vessel sizes from 0.7 L to 4 L.
Eppendorf BioBLU 10c Single-Use Vessels Simplify Handling of Cell Culture Bioprocesses - BioProcess International
Substituting traditional glass bioreactors with single-use equipment can simplify a bioprocess workflow. Implementing single-use vessels eliminates the need for cleaning and autoclaving, thus reducing the time needed to prepare a bioprocess run and lowering contamination risk. Another advantage is that single-use vessels reduce occupational hazards associated with overweight handling (especially at larger bench scales) because plastic weighs less than glass.
Cell Culture Bioprocessing in Perfusion: Assessing Cell Retention Technologies - BioProcess International
Upstream bioprocessing in perfusion mode holds great promise for industrial production of cells and biologics. In perfusion, fresh medium is added constantly to the bioreactor, and used medium is harvested while the cells are retained in the bioreactor. As a result, the composition of the cell culture medium stays quite constant during the process. This offers several advantages.
Comparing Culture Methods in Monoclonal Antibody Production: Batch, Fed-Batch, and Perfusion
Recombinant protein manufacturing with Chinese hamster ovary (CHO) cells represents over 70% of the entire biopharmaceutical industry (1). In fact, human monoclonal antibodies (hMAbs) produced by CHO cells have played a major role in both the diagnostic and therapeutic markets for decades. One of the first human–mouse chimeric MAbs to obtain FDA approval was Roche’s rituximab treatment for non-Hodgkin’s lymphoma, chronic lymphocytic leukemia, and rheumatoid arthritis.
Show More
loading
Actions
Is this you?
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Get in touch with Amanda
Contact Amanda, search articles and posts on X, monitor coverage, and track replies from one place.
Learn more about Muck Rack