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Epithelioid haemangioendothelioma (EHE) of bone often presents as a multifocal tumour with an affinity for cortical bone. Therefore, pathological fractures are common at presentation. They can be confused initially for metastatic carcinoma, given their potential to express cytokeratins. However, the diagnosis can now be clarified with to the discovery of a unique translocation that is found in the majority of EHE tumours.
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