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Articles by Amy Milton
Mind over metabolism: a systematic review of GLP-1 receptor agonists in the treatment of stress-related disorders
Abstract Depression and post-traumatic stress disorder (PTSD) are highly prevalent and debilitating stress-related psychiatric disorders, yet current pharmacological treatments fail to provide meaningful benefit for approximately half of patients. Converging evidence implicates metabolic dysregulation across psychiatric disorders, highlighting metabolic pathways as novel therapeutic targets.
Drug memory reconsolidation: from molecular mechanisms to the clinical context - Translational Psychiatry
Abstract Since its rediscovery at the beginning of the 21st Century, memory reconsolidation has been proposed to be a therapeutic target for reducing the impact of emotional memories that can go awry in mental health disorders such as drug addiction (substance use disorder, SUD). Addiction can be conceptualised as a disorder of learning and memory, in which both pavlovian and instrumental learning systems become hijacked into supporting drug-seeking and drug-taking behaviours.
To catch a memory through covert ops
Disrupting reconsolidation of the maladaptive memories underlying post-traumatic stress disorder (PTSD) could be transformative for treatment. However, patients cannot undergo the direct re-exposure to trauma-cues used to induce reconsolidation in animal studies. Ressler and colleagues report ‘covert’ memory reactivation in rats, bolstering hopes for translation of reconsolidation-based interventions.
Removed
A sell-out hit at Belfast Children’s Festival, Baboro Festival and Dublin Theatre Festival, Removed comes to the Traverse Festival. Removedis the funny, poignant and affecting story of Adam that offers a glimpse into the unknown experiences of growing up as a "Looked After" child.
Amy Milton: Can we edit memories?
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