Abstract To explore the potential of an adult rabbit descemetorhexis model to recapitulate the damage to the endothelium and Descemet’s membrane (DM) seen in humans. Five corneas of 5 female New Zealand rabbits aged 24–26 months underwent 5-mm descemetorhexis; five unwounded corneas from 5 rabbits served as controls. Animals were followed up for 12-week and post-surgical clinical evaluation was performed using slit-lamp, macro images, and optical coherence tomography (OCT).
