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Articles by Anders Näär
Student Spotlight: Yesim Goktekin
Yesim Goktekin moved from Istanbul, Turkey, to the East Coast during the mid-90s to pursue a master's in construction management. She relocated to the Bay Area for work after graduating, met her husband (who was then a PhD student at UC Berkeley), and started a family. But after having worked in construction management for more than two decades, Goktekin decided it was time for a change.
SARS-CoV-2 Spike triggers barrier dysfunction and vascular leak via integrins and TGF-β signaling - Nature Communications
Abstract Severe COVID-19 is associated with epithelial and endothelial barrier dysfunction within the lung as well as in distal organs. While it is appreciated that an exaggerated inflammatory response is associated with barrier dysfunction, the triggers of vascular leak are unclear.
An intranasal ASO therapeutic targeting SARS-CoV-2 - Nature Communications
Abstract The COVID-19 pandemic is exacting an increasing toll worldwide, with new SARS-CoV-2 variants emerging that exhibit higher infectivity rates and that may partially evade vaccine and antibody immunity. Rapid deployment of non-invasive therapeutic avenues capable of preventing infection by all SARS-CoV-2 variants could complement current vaccination efforts and help turn the tide on the COVID-19 pandemic.
Researchers discover link between microRNA and metabolic disorders
In a study published today in the journal Cell, UC Berkeley Nutritional Sciences and Toxicology professor Anders Näär led a group of researchers from 12 institutions in the United States and Europe, to better understand a region on the second human chromosome previously linked to both the digestion of milk and metabolic disorders.
A lipid-free and insulin-supplemented medium supports De Novo fatty acid synthesis gene activation in melanoma cells
Loading metrics Open Access Peer-reviewed Research Article Su Wu , Anders M. Näär Su Wu, Anders M. Näär Published: April 10, 2019 https://doi.org/10.1371/journal.pone.0215022 Figures Abstract While investigating the role played by de novo lipid (DNL) biosynthesis in cancer cells, we sought a medium condition that would support cell proliferation without providing any serum lipids.
Insulin insights
The discovery of insulin in the 1920s marked the breakthrough in the almost 3,500-year-long mystery of diabetes, a disease first described in ancient Egyptian papyruses. Until its discovery, physicians struggled to explain how symptoms such as sugary urine, constant thirst and frequent urination could lead to ailments ranging from blindness and nerve damage to coma and death.
Näär receives $9.2 million Novo Nordisk Foundation grant
An international research team co-led by Anders Näär has received $9.2 million from the Novo Nordisk Foundation’s Challenge 2018 Program to advance development of new therapies for the treatment of nonalcoholic steatohepatitis (NASH). Näär is a professor of metabolic biology and vice chair of the Department of Nutritional Sciences and Toxicology.
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