To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. Figure 1 Mean changes (± SEM) from baseline in the 25-item Hamilton Depression Rating Scale scores (ΔHDRS), the mean Visual Analog Scale “high” scores (VAS-high), and mean positive symptom scores of the Brief Psychiatric Rating Scale (BPRS-positive) after ketamine (.5 mg/kg over 40 min) and saline infusions in seven subjects completing both treatment conditions.