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1. Introduction Over the past decade, an increasing number of innovative medicines have obtained marketing authorisation in multiple indications. Predominantly, this trend is noticeable in the oncology space driven by research in immuno-oncology, specifically research in immune checkpoint inhibitors such as PD-1 and PD-L1 inhibitors, where drugs have demonstrated efficacy across a large number of indications. As described in depth by Lawlor et al.
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