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Articles by Anke Leichtle
Perceived sound quality and speech recognition are not interchangeable outcome measures in adult cochlear implant users
Abstract Introduction: This study examined whether descriptor-based reports of perceived sound quality in adult cochlear implant users are associated with speech-recognition outcomes, preoperative maximum monosyllabic word recognition, and patient- or device-related factors.
Bacterial and fungal communities and network dynamics in Otitis media patients upon 1,8-Cineol treatment
Abstract The present study investigated the bacterial and fungal communities and cross-domain network interactions in patients with chronic Otitis media in response to the natural monoterpene medicinal 1,8-Cineol as a promising treatment option. While the bacterial community showed modest changes with preserved core genera, the fungal community underwent dramatic diversification and network expansion.
Precise ablation of cholesteatoma using a 445-nm diode laser
Abstract In cholesteatoma surgery, precise tissue resection is important, as the diseased tissue needs to be completely removed while preserving the ossicular chain to prevent recurrence and hearing loss. The ability to precisely ablate tissue using a pulsed \(445 nm\) diode laser operating in single-trigger mode was investigated. Single laser pulses with a duration of \(100 ms\) were applied with a power ranging from \(0.5 \text{to} 4 W\) via a multimode optical fiber.
Partial recovery of peripheral blood monocyte subsets in head and neck squamous cell carcinoma patients upon radio(chemo)therapy is associated with decreased plasma CXCL11 | BMC Cancer | Full Text
All patients were treated at the Department of Otorhinolaryngology, University Hospital Schleswig-Holstein, Campus Luebeck, and have given their written informed consent. The study was approved by the local ethics committee of the University of Luebeck (approval number 16–278) and conducted in accordance with the ethical principles for medical research formulated in the WMA Declaration of Helsinki.
1,8-Cineol Attenuates Checkpoint Molecule PDL-1 and Adhesion Molecule CX3CR1 in Circulating Monocytes in Otitis Media Patients
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Hinnerk Schulz-Hildebrandt
Dynamic Microscopic Optical Coherence Tomography as a New Diagnostic Tool for Otitis Media June 14, 2023 | Otolaryngology | Harvard University, Massachusetts General Hospital, University of Lübeck Hypothesis: Otitis media (OM) can be successfully visualized and diagnosed by dynamic microscopic optical coherence tomography (dmOCT). Background: OM is one of the most common infectious diseases and, according to the WHO, one of the leading health problems with high mortality in developing countries.
Dynamic Microscopic Optical Coherence Tomography as a New Diagnostic Tool for Otitis Media
This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Modes of Action of 1,8-Cineol in Infections and Inflammation
Abstract : The monoterpene 1,8-Cineol is a natural plant-based therapeutic agent that is commonly applied to treat different inflammatory diseases due to its mucolytic, anti-microbial and anti-inflammatory properties. It has become increasingly clear in the recent years that 1,8-Cineol spreads almost everywhere in the human body after its oral administration, from the gut to the blood to the brain.
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