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Articles by Anna Munke
High-throughput in situ single particle X-ray imaging of dehydrating viral capsids
Abstract Single-stranded RNA viruses co-assemble their capsid with the genome, and variations in capsid structures can have significant functional relevance. In particular, viruses need to respond to a dehydrating environment to prevent genomic degradation and remain active upon rehydration. Theoretical work has predicted low-energy buckling transitions in icosahedral capsids, which could protect the virus from further dehydration.
Advancing time-resolved structural biology: latest strategies in cryo-EM and X-ray crystallography - Nature Methods
Abstract Structural biology offers a window into the functionality of molecular machines in health and disease. A fundamental challenge lies in capturing both the high-resolution structural details and dynamic changes that are essential for function. The high-resolution methods of X-ray crystallography and electron cryo-microscopy (cryo-EM) are mainly used to study ensembles of static conformations but can also capture crucial dynamic transition states.
Structure of the T=13 capsid of infectious pancreatic necrosis virus (IPNV) - a salmonid birnavirus
Abstract Birnaviruses infect a broad range of vertebrate hosts, including fishes and birds, and cause substantial economic losses in the fishery and livestock industries. The infectious pancreatic necrosis virus (IPNV), an aquabirnavirus, specifically targets salmonids.
High-resolution comparative atomic structures of two Giardiavirus prototypes infecting G. duodenalis parasite
Loading metrics Open Access Peer-reviewed Research Article ? This is an uncorrected proof. Citation: Wang H, Marucci G, Munke A, Hassan MM, Lalle M, Okamoto K (2024) High-resolution comparative atomic structures of two Giardiavirus prototypes infecting G. duodenalis parasite. PLoS Pathog 20(4): e1012140. https://doi.org/10.1371/journal.ppat.1012140 Editor: Félix A.
High-resolution comparative atomic structures of two Giardiavirus prototypes infecting G.duodenalis parasite
Abstract Giardia lamblia virus (GLV) is a non-enveloped icosahedral dsRNA virus and an endosymbiont virus infecting the zoonotic protozoan parasite Giardia duodenalis (syn. G. lamblia, G. intestinalis), a pathogen of mammals, including humans. Elucidating the transmission mechanism of GLV is crucial to an in-depth understanding of the virulence of the virus in G. duodenalis.
Capsid Structure of a Marine Algal Virus of the Order Picornavirales
Structure and Assembly | Spotlight Anna Munke, Kei Kimura, Yuji Tomaru, Kenta Okamoto Julie K. Pfeiffer, Editor DOI: 10.1128/JVI.01855-19 ABSTRACT The order Picornavirales includes viruses that infect different kinds of eukaryotes and that share similar properties.
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