These must-read books set in Pennsylvania include modern classics and bestselling fiction, many of which have been made into major motion pictures. Visit the Keystone State with these books that take place in Pennsylvania. 1. Rabbit, Run by John Updike “Harry Angstrom was a star basketball player in high school and that was the best time of his life. Now in his mid-20s, his work is unfulfilling, his marriage is moribund, and he tries to find happiness with another woman.