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Articles by Anne Pizard
Beneficial Impact of Eicosapentaenoic Acid on the Adverse Effects Induced by Palmitate and Hyperglycemia on Healthy Rat Chondrocyte
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In need of signalling pathway data
Corresponding Author E-mail address:anne.pizard@inserm.fr Inserm 1024, Institut de Biologie de l'École Normale Supérieure (IBENS), PSL University of Paris, Paris, France; CHRU‐Nancy, Vandoeuvre‐lès‐NancyFrance Corresponding author. Inserm 1024, Institut de Biologie de l'École Normale Supérieure (IBENS), PSL University of Paris, 46 rue d'Ulm, 75005 Paris, France; CHRU‐Nancy, rue du Morvan, 54500 Vandoeuvre‐lès‐Nancy, France.
Tailoring mineralocorticoid receptor antagonist therapy in heart failure patients: are we moving towards a personalized approach?
The aim of personalized medicine is to offer a tailored approach to each patient in order to provide the most effective therapy, while reducing risks and side effects. The use of mineralocorticoid receptor antagonists (MRAs) has demonstrated major benefits in heart failure with reduced ejection fraction (HFrEF), results with challenging inconsistencies in heart failure with preserved ejection fraction (HFpEF), and ‘neutral’ preliminary results in acute heart failure.
Myocardial fibrosis: biomedical research from bench to bedside
Myocardial fibrosis refers to a variety of quantitative and qualitative changes in the interstitial myocardial collagen network that occur in response to cardiac ischaemic insults, systemic diseases, drugs, or any other harmful stimulus affecting the circulatory system or the heart itself.
Proteomic and Mechanistic Analysis of Spironolactone in Patients at Risk for HF:
Abstract Objectives This study sought to further understand the mechanisms underlying effect of spironolactone and assessed its impact on multiple plasma protein biomarkers and their respective underlying biologic pathways. Background In addition to their beneficial effects in established heart failure (HF), mineralocorticoid receptor antagonists may act upstream on mechanisms, preventing incident HF.
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