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Articles by Anwar Baban
Timothy syndrome and CACNA1C-Related Disorder: first international language and management guidelines consensus statement
Abstract Timothy syndrome is a multisystemic genetic disorder, classically characterised by prolonged QT interval and subsequent cardiac arrhythmias, neurodevelopmental disorders including developmental delay and autism and syndactyly or hip dysplasia. It is caused by variants in the CACNA1C gene, which encodes the widely expressed Cav1.2 voltage-gated calcium channel. Since its characterisation in 2004, the number of variants in CACNA1C associated with Timothy syndrome has expanded.
Impairment of Innate Immunity and Depletion of Vaccine‐Induced Memory B and T Cells in the Absence of the Spleen
1 Introduction The spleen is not indispensable for survival, but splenectomy is associated with an increased risk of bacteriemia and fulminant sepsis by encapsulated bacteria, such as Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenza [1]. Antibiotic prophylaxis and vaccination represent the main preventive tools. Guidelines recommend vaccination either before or 2 weeks after splenectomy [2-4].
Unique Features of Cardiovascular Involvement and Progression in Children with Marfan Syndrome Justify Dedicated Multidisciplinary Care
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Self- and proxy-reported impaired social interaction in young adults with simple congenital heart defects
Sara Hirani Lau-Jensen1,2* Benjamin Asschenfeldt3 Lars Evald4 Vibeke E.
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