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Articles by Aref Pariz
A Computational Framework for Myelin as a Regulator of Temporal Integration, Neuronal Excitability, and Synaptic Plasticity
1 Introduction Myelin wraps around axonal membranes and plays a fundamental role in neural signaling. By enabling saltatory conduction—which dramatically increases conduction velocity (CV)—myelin can adjust for variability in length and caliber between different axons (Salami et al. 2003; Seidl 2014; Swadlow et al. 1978; Swadlow and Waxman 2012). Moreover, myelin production by oligodendrocytes (OLs) is modulated by neuronal activity (Gibson et al. 2014; Mount and Monje 2017; Osso and Hughes 2024).
Nanozymatic platform for dual colorimetric and fluorimetric sensing of H₂O₂ and glucose using Ni-CoWO₄ nanoparticles
Abstract Hydrogen peroxide (H₂O₂) plays a crucial role in both biological and industrial systems. Excessive H₂O₂ can lead to oxidative stress, cellular damage, and process-related issues in manufacturing. For this reason, fast and sensitive detection methods are needed. In this study, Ni-CoWO₄ nanoparticles, belonging to the bimetallic nanozymes family, were used as catalysts to promote the oxidation of ortho-phenylenediamine (OPD) by H₂O₂.
Amplifying post-stimulation oscillatory dynamics by engaging synaptic plasticity with periodic stimulation: a modelling study
Abstract Periodic brain stimulation (PBS) techniques, either intracranial or non-invasive, electrical or magnetic, represent promising neuromodulatory tools for the treatment of neurological and neuropsychiatric disorders. Through the modulation of endogenous oscillations, PBS may engage synaptic plasticity, hopefully leading to persistent lasting effects.
Morphological variability may limit single-cell specificity to electric field stimulation
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Selective control of synaptic plasticity in heterogeneous networks through transcranial alternating current stimulation (tACS)
Directional tACS-induced synaptic plasticity in a heterogeneous cortical layer To generalize our observations, we analyzed a sparse network of N = 10, 000 LIF neurons, modeling the response of a neuronal population, representing a single cortical layer, to tACS (see Material and methods). We characterized the influence of timescale heterogeneity amongst cell types on intra-laminar synaptic recruitment by periodic stimulation and the dependence on its frequency.
Transmission delays and frequency detuning can regulate information flow between brain regions
Loading metrics Open Access Peer-reviewed Research Article Aref Pariz, Ingo Fischer, Alireza Valizadeh , Claudio Mirasso Aref Pariz, Ingo Fischer, Alireza Valizadeh, Claudio Mirasso Published: April 15, 2021 https://doi.org/10.1371/journal.pcbi.1008129 Figures Abstract Brain networks exhibit very variable and dynamical functional connectivity and flexible configurations of information exchange despite their overall fixed structure.
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