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Articles by Arfon GMT Powell
Gongs galore: phaleristic study of the relative risk of a healing art related New Year Honour
Gongs galore: phaleristic study of the relative risk of a healing art related New Year Honour http://orcid.org/0000-0002-3556-5701Katie Mellor1, http://orcid.org/0000-0002-3740-8275Arfon GMT Powell1,2, http://orcid.org/0000-0002-1986-1391Osian P James1, http://orcid.org/0000-0003-1087-744XDavid B Robinson1, http://orcid.org/0000-0003-1218-9907Luke Hopkins1,3, Richard John Egan3,4, Wyn G Lewis1 1 School of Surgery, NHS Wales Health Education and Improvement Wales, Nantgarw, UK 2 Division of...
Gongs galore: phaleristic study of the relative risk of a healing art related New Year Honour
Gongs galore: phaleristic study of the relative risk of a healing art related New Year Honour http://orcid.org/0000-0002-3556-5701Katie Mellor1, http://orcid.org/0000-0002-3740-8275Arfon GMT Powell1,2, http://orcid.org/0000-0002-1986-1391Osian P James1, http://orcid.org/0000-0003-1087-744XDavid B Robinson1, http://orcid.org/0000-0003-1218-9907Luke Hopkins1,3, Richard John Egan3,4, Wyn G Lewis1 1School of Surgery, NHS Wales Health Education and Improvement Wales, Nantgarw, UK 2Division of...
Gongs galore: phaleristic study of the relative risk of a healing art related New Year Honour
Gongs galore: phaleristic study of the relative risk of a healing art related New Year Honour http://orcid.org/0000-0002-3556-5701Katie Mellor1, http://orcid.org/0000-0002-3740-8275Arfon GMT Powell1,2, http://orcid.org/0000-0002-1986-1391Osian P James1, http://orcid.org/0000-0003-1087-744XDavid B Robinson1, http://orcid.org/0000-0003-1218-9907Luke Hopkins1,3, Richard John Egan3,4, Wyn G Lewis1 1School of Surgery, NHS Wales Health Education and Improvement Wales, Nantgarw, UK 2Division of...
ERK and p38MAPK combine to improve survival in patients with BRAF mutant colorectal cancer
In colorectal cancer (CRC), BRAF mutations influence tumour progression. In mismatch repair-deficient (dMMR) tumours, BRAF mutations are associated with a good prognosis, whereas in MMR-competent tumours, they are detrimental. The differential expression of the downstream MAPK pathway members, which are constitutively activated in BRAF mutant patients, may account for these differences. Phosphorylation of ERK, p38MAPK and JNK was assessed by immunohistochemistry, utilising CRC tissue microarrays.
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