Convergence and Technologies Shirin Elizabeth Khorsandi, Arran D. Dokal, Vinothini Rajeeve, David J. Britton, Megan S. Illingworth, Nigel Heaton and Pedro R. Cutillas DOI: 10.1158/0008-5472.CAN-21-0955 Published November 2021 Abstract Cholangiocarcinoma is a form of hepatobiliary cancer with an abysmal prognosis. Despite advances in our understanding of cholangiocarcinoma pathophysiology and its genomic landscape, targeted therapies have not yet made a significant impact on its clinical management.