Prurigo nodularis (PN), being a subtype of chronic prurigo, is defined as a chronic skin disorder characterized by the presence of highly pruritic, hyperkeratotic nodules that occur due to neuronal sensitization to itch and the development of an itch-scratch-itch cycle.1 The pathogenesis of PN remains unclear, but the involvement of T-helper (Th) 1, Th2, Th17 and Th22 pathways has been implicated.2, 3 Data from clinical trials on the efficacy of biological drugs blocking interleukin (IL) 4,...
