1 INTRODUCTION Chromodomain helicase DNA-binding protein 2 (CHD2, MIM: 602119) is a member of the CHD family, which comprises an SNF2-related helicase/ATPase domain and a chromatin-remodelling domain (chromodomain) (Lamar & Carvill, 2018). The CHD family of proteins affects the expression of genes by modification of chromatin structure, leading to alterations of the accessibility of transcriptional regulators to the DNA template (Liu et al., 2015; Wilson et al., 2021).
