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A dental implant-on-a-chip for 3D modeling of host–material–pathogen interactions and therapeutic testing platforms† Atul Dhall, a Jun Ying Tan,b Min Jun Oh,ac Sayemul Islam,df Jungkwun Kim,*be Albert Kim *df and Geelsu Hwang *ag Abstract The precise spatiotemporal control and manipulation of fluid dynamics on a small scale granted by lab-on-a-chip devices provide a new biomedical research realm as a substitute for in vivo studies of host–pathogen interactions.
Cerium oxide nanoparticles (CeNPs) are potent reactive oxygen and nitrogen species scavengers and demonstrate beneficial antioxidant properties in both cell culture and animal studies. However, their environmental fate, particularly in animals, is still under investigation. Studies have shown that CeNPs at very high doses can be retained briefly in organs such as the liver and in the bone marrow.
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