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Background: Breast cancer (BC) is the leading cause of cancer-related mortality in women worldwide. Changes in DNA methylation in peripheral blood could be associated with malignancy at early stage. However, the BC-associated DNA methylation signatures in peripheral blood were largely unknown. Methods: Illumina 27K Methylation Array and Illumina 450K Methylation Array for the discovery of BC-related aberrant methylation sites in peripheral blood.
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