The study by Wornes and colleagues published in this issue addresses a gap that has persisted in Australian nuclear medicine practice for over half a century. Their derivation of a 99ᵐTc-pertechnetate thyroid uptake reference range of 0.4%–2.4% from a consecutive cohort of 151 euthyroid adults at a Victorian quaternary centre is, to the authors' knowledge and our own, the first such dataset published for an Australian population [1]. The reference range of 1%–4% against which Wornes et al.