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Abstract Genetic inactivation of alpha-galactosidase A (GLA) causes Fabry disease, which is characterized by early cutaneous lesions such as angiokeratomas. However, the role of GLA in malignancies like melanoma remains poorly understood. Here, we show that high expression of GLA correlates with tumor development and progression, including in melanoma.
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.