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Articles by Barbara Morley
Alpha9alpha10 knockout mice show altered physiological and behavioral responses to signals in masking noise
Abstract Medial olivocochlear (MOC) efferents modulate outer hair cell motility through specialized nicotinic acetylcholine receptors to support encoding of signals in noise. Transgenic mice lacking the alpha9 subunits of these receptors (a9KOs) have normal hearing in quiet and noise, but lack classic cochlear suppression effects and show abnormal temporal, spectral, and spatial processing.
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