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1. Introduction Urothelial bladder cancer (UBC) is the ninth most prevalent cancer worldwide, with yearly over 500 000 new cases and 200 000 attributable deaths [ [1] Bray F. Ferlay J. Soerjomataram I. Siegel R.L. Torre L.A. Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. ].
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