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Articles by Bender Ignacio
Correction: How would Marie Kondo design a protocol? In favor of subtractive change in clinical trials
A Correction on How would Marie Kondo design a protocol? In favor of subtractive change in clinical trials by Bender Ignacio, R., Rowan, K., and Cook, D. (2026). Front. Med. 13:1776929. doi: 10.3389/fmed.2026.1776929 The title of this article was erroneously given as: “How would Mari Kondo design a protocol? In favor of subtractive change in clinical trials”. The correct title of the article is “How would Marie Kondo design a protocol? In favor of subtractive change in clinical trials”.
How would Mari Kondo design a protocol? In favor of subtractive change in clinical trials
Complexities in contemporary clinical trials are frequently self-defeating relative to the goals of clinical research—namely to inform and improve care for as many patients as possible. Trials need to be rigorous, relevant, ethical, inclusive, feasible and affordable. Trials require broad access to research participation to optimize the generalizability of results and influence practice and improve outcomes for diverse populations.
Long-acting Injectable Containing Lopinavir Eliminates Reliance on Ritonavir Pharmacokinetic Enhancement
High-extraction protease inhibitors (e.g., for HIV and COVID-19) typically require ritonavir to enhance bioavailability by overcoming first-pass metabolism. However, in the long-acting subcutaneous injectable dosage form TLC-ART 101, lopinavir persisted in plasma for 57 days, while ritonavir was detectable for only 3–7 days.
Durable preservation of antiviral antibodies after CD19-directed chimeric antigen receptor T-cell immunotherapy
IMMUNOBIOLOGY AND IMMUNOTHERAPY| November 19, 2019
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