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Altered Iron and Microstructure in Huntington's Disease Subcortical Nuclei: Insight From 7T MRI
Huntington's disease (HD) is a monogenic neurodegenerative disorder caused by cytosine-adenine-guanine (CAG) repeat expansion (≥36) in the huntingtin (HTT) gene.1 While subjects at risk of HD can be identified using genetic testing, the length of CAG repeats only accounts for up to 50%–70% of the variance in age of onset and is less predictive in patients with a relatively low number of repeats.2 Moreover, CAG repeat length has also been shown to be insufficient in explaining the high...
The influence of spatially heterogeneous anthropogenic change on bill size evolution in a coastal songbird
Abstract Natural history collections provide an unparalleled resource for documenting population responses to past anthropogenic change. However, in many cases, traits measured on specimens may vary temporally in response to a number of different anthropogenic pressures or demographic processes.
Everyday illiberalism: How Hungarian subnational politics propel single‐party dominance
ORIGINAL ARTICLE Funding information: Hertelendy Graduate Fellowship in Hungarian Studies Get access to the full version of this article. View access options below. If you have previously obtained access with your personal account, Please log in. Item saved, go to cart Details Unlimited viewing of the article/chapter PDF and any associated supplements and figures. Article/chapter can be printed. Article/chapter can be downloaded. Article/chapter can not be redistributed.
Direct Evidence for the Polymeric Nature of Polydopamine
The full text of this article hosted at iucr.org is unavailable due to technical difficulties. Communication Direct Evidence for the Polymeric Nature of Polydopamine Prof. Phillip B.
The impact of bacteriophages on phyllosphere bacterial abundance and composition
Interactions between bacteria and bacteriophage viruses (phages) are known to influence pathogen growth and virulence, microbial diversity, and even biogeochemical cycling. Lytic phages in particular infect and lyse their host cells, and can therefore have significant effects on cell densities as well as competitive dynamics within microbial communities.
Characterization and stratification of prostate lesions based on comprehensive multiparametric MRI using detailed whole-mount histopathology as a reference standard - Starobinets - 2017 - NMR in Biomedicine - Wiley Online Library
The purpose of this study was to characterize prostate cancer (PCa) based on multiparametric MR (mpMR) measures derived from MRI, diffusion, spectroscopy, and dynamic contrast-enhanced (DCE) MRI, and to validate mpMRI in detecting PCa and predicting PCa aggressiveness by correlating mpMRI findings with whole-mount histopathology. Seventy-eight men with untreated PCa received 3 T mpMR scans prior to radical prostatectomy.
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