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Summary Background Drugs modifying angiotensin II signalling could reduce Alzheimer's disease pathology, thus decreasing the rate of disease progression. We investigated whether the angiotensin II receptor antagonist losartan, compared with placebo, could reduce brain volume loss, as a measure of disease progression, in clinically diagnosed mild-to-moderate Alzheimer's disease.
Loading metrics Open Access Peer-reviewed Research Article Jill Shawe, Dilisha Patel , Mark Joy, Beth Howden, Geraldine Barrett, Judith Stephenson Jill Shawe, Dilisha Patel, Mark Joy, Beth Howden, Geraldine Barrett, Judith Stephenson Published: March 20, 2019 https://doi.org/10.1371/journal.pone.0213897 Figures Abstract Methods A cross-sectional survey of men attending antenatal care with their partners at three London Maternity Units.
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