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Articles by Bin Pan
Organelle associations and metabolic rewiring of size-defined hepatic lipid droplets
Abstract Lipid droplet (LD) size is a key determinant of hepatic lipid metabolism, yet the molecular programming routing size-defined subpopulations to distinct fates remains unclear. Here we show that a fractionation workflow resolves hepatic LDs by size and organelle association, defining a high-confidence intrinsic LD proteome.
NLRP3 signalling in NSCLC: distinguishing expression, inflammasome activation and context-dependent function
Abstract Non-small cell lung cancer (NSCLC) remains a major cause of cancer-related mortality despite advances in targeted therapy and immune checkpoint blockade. NLRP3-associated inflammation has attracted increasing interest in NSCLC, yet interpretation of the available evidence remains challenging because molecular expression, inflammasome activation, cytokine processing, pyroptotic execution and pathway dependence are frequently considered together.
Emission strategies of conglomerates: pollution emission and transfer mechanisms under energy regulation
Abstract Conglomerates constitute a core component of modern economies and play a pivotal role in resource allocation. Using China’s “Top 1,000” energy conservation program as an exogenous policy shock, this paper employs a difference-in-differences design based on manufacturing firm panel data to investigate how energy regulation affects intra-conglomerate pollution strategies.
Synergistic Regulation of Soil Function and Wind Erosion Resistance by Sand Barriers, Vegetation, and Artificial Biological Crust in the Tengger Desert
1 Introduction Desertification, as a core driver of ecosystem degradation in arid regions globally, has led to widespread environmental and socioeconomic challenges.
Decoding α -MoC 1− x Nanoparticle Formation in Continuous Flow via Machine Learning
1 Introduction Transition metal carbides are emerging as cost-effective alternatives to noble metals in heterogeneous catalysis owing to their comparable electronic structures, high thermal and chemical stability, and high catalytic activity [1-4]. Among them, molybdenum carbides display outstanding catalytic performance across diverse reactions, inducing hydrogen evolution [5], CO2 hydrogenation [6], hydrodeoxygenation [7], and reforming processes [8].
Phenology-guided deep learning for automated rice mapping using SAR time-series imagery
?Mathematical formulae have been encoded as MathML and are displayed in this HTML version using MathJax in order to improve their display. Uncheck the box to turn MathJax off. This feature requires Javascript. Click on a formula to zoom. Abstract Accurate and timely rice mapping at regional scales is essential for global food security monitoring, agricultural policy development, and sustainable intensification efforts.
Genetics and pathophysiology of diffuse idiopathic skeletal hyperostosis
Abstract Diffuse Idiopathic Skeletal Hyperostosis (DISH) is a systemic condition primarily characterized by flowing ossification along the anterolateral aspects of the spine, often leading to back pain, dysphagia, and an increased risk of spinal fractures. Despite its significant clinical burden and high prevalence among the elderly, DISH remains underdiagnosed and poorly understood, with no disease-modifying therapies currently available.
Imaging Features of Lung Ground-Glass Nodules and Their Correlation With Biological Behavior
Specialty Please choose I'm not a medical professional. Allergy and Immunology Anatomy Anesthesiology Biostatistics Cardiac/Thoracic/Vascular Surgery Cardiology Critical Care Dentistry Dermatology Diabetes and Endocrinology Emergency Medicine Epidemiology and Public Health Family Medicine Forensic Medicine Gastroenterology General Practice Genetics Geriatrics Health Policy Hematology HIV/AIDS Hospital-based Medicine I'm not a medical professional.
Landslide susceptibility mapping using extended random forest architecture with PS‐InSAR‐based optimisation
CONFLICT OF INTEREST STATEMENT The authors declare no conflicts of interest. DATA AVAILABILITY STATEMENT The data are based on ongoing PhD research and can be provided upon reasonable request. REFERENCES & (2020) How do machine learning techniques help in increasing accuracy of landslide susceptibility maps? Geoscience Frontiers, 11(3), 871–883. Available from: https://doi.org/10.1016/j.gsf.2019.10.001 , , , , , , et al.
Asymmetric Synthesis of Dihydrocoumarins via Squaramide‐Catalyzed [4 + 2] Annulation Reaction of 2‐Hydroxy α‐Amido Sulfones and Azlactones
Conflict of Interests The authors declare no conflict of interest. Supporting Information Filename Description asia70334-sup-0001-SuppMat.docx6.1 MB Supporting Information References 1a) , , , , , , , , , , , Food Chem. Toxicol. 1998, 36, 249–278; b) , , , , , J. Med. Chem. 2004, 47, 2635–2644; c) , , , , , J. Nat. Prod. 2005, 68, 1180–1184; d) , , , , , Curr. Med. Chem. 2005, 12, 887–916; e) , , , , , J. Nat. Prod. 2007, 70, 2010–2013; f) , , , Curr. Med. Chem. 2008, 15, 2664–2679; g) , , , , Curr. Med. Chem.
NIR Light‐Controlled Cascade Regulation of Mixed‐Valence Copper (I)/(II) Nanozyme (Cu2−xSe) Spray for Infectious Wound Healing
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The Role and Phagocytic Mechanisms of Alveolar Macrophages in Inflammatory Responses Induced by Diesel Exhaust Particles
Ecotoxicology and Public HealthJuly 16, 2025 Dongyang Han Department of Environmental Health, School of Public Health, Fudan University, Shanghai 200032, China Renzhen Peng Department of Environmental Health, School of Public Health, Fudan University, Shanghai 200032, China Bin Pan Department of Environmental Health, School of Public Health, Fudan University, Shanghai 200032, China NHC Key Lab of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), School of Pharmacy,...
Sustainability-Driven Corporate Behaviours: Insights from Regulation, Disclosure, Climate Risk, and Market Responses
IdiomacatalàDeutschEnglishespañoleuskarafrançaisgalegoitalianoportuguêsromână
Bio-Inspired Single-Atom Nanozymes for Microplastic Degradation
Bio-Inspired Single-Atom Nanozymes for Microplastic Degradation Copper single-atom-loaded graphitic nitride nanozymes (Cu SAs) were constructed by bio-inspired rational design from natural laccase and density functional theory calculations. Theoretical investigation revealed the geometrical and electronic structural advantages of the Cu-N active center.
Accelerating Consensus Reaching Through Top Persuaders: A Social Persuasion Model in Social Network Group Decision Making
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Detection of Impedance Inhomogeneity in Lithium-Ion Battery Packs Based on Local Outlier Factor
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Visible light-induced strain-release transformations of bicyclo[1.1.0]butanes
Visible light-induced strain-release transformations of bicyclo[1.1.0]butanes Bicyclo[1.1.0]butanes, as structurally unique compounds with high strained energy and diverse chemical properties, are becoming increasingly popular building blocks in organic and pharmaceutical chemistry. Strain-release transformation of bicyclo[1.1.0]butanes has received great attention from chemists as its atom- and step-economy, and significant achievements have been made in this field.
Construction of a High-Resolution Waterlogging Disaster Monitoring Framework Based on the APSIM Model: A Case Study of Jingzhou and Bengbu
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Visible‐Light‐Mediated [2+2] Photocycloadditions of Alkynes
Visible-light-mediated [2+2] photocycloaddition reaction can be considered an ideal solution due to its green and sustainable properties, and is one of the most efficient methods to synthesize four-membered ring motifs. Although research on the [2+2] photocycloaddition of alkynes is challenging because of the diminished reactivity of alkynes, and the more significant ring strain of the products, remarkable achievements have been made in this field.
TPI1 promotes MAPK/ERK‐induced EMT, cell migration and invasion in lung adenocarcinoma
INTRODUCTION Lung cancer is one of the most common cancers globally,1, 2 with approximately 85% of cases classified as non-small cell lung cancer (NSCLC). NSCLC subtypes include lung squamous cell carcinoma (LUSC), lung adenocarcinoma (LUAD) and large cell lung carcinoma.
Fusing Ascending and Descending Time-Series SAR Images with Dual-Polarized Pixel Attention UNet for Landslide Recognition
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Direct osteogenesis and immunomodulation dual function via sustained release of naringin in the polymer scaffold
Direct osteogenesis and immunomodulation dual function via sustained release of naringin in the polymer scaffold ABSTRACT： Many traditional Chinese medicines monomers, such as naringin (NG), can regulate the local immune microenvironment to benefit osteogenesis. However, the rapid release of NG in scaffolds severely influences the osteogenesis-promoting effect.
Utilizing the intelligent sensing function of conjugated materials to create intelligent flute training equipment
1 Introduction Flute is a professional instrument, an art, and a music discipline. Flute training requires music students to practice and persist for a long time in order to acquire good performance skills and expressive abilities. However, in traditional flute practice, the use of equipment brings many challenges and limitations, such as difficulty in maintenance and adjustment. Learners often rely on feedback from mentors and their own feelings in order to perform correctly.
A Multistep, Multicomponent Extraction and Separation Microfluidic Route to Recycle Water-Miscible Ionic Liquid Solvents
Download Hi-Res ImageDownload to MS-PowerPointCite This:Ind. Eng. Chem. Res. 2023, XXXX, XXX RETURN TO ARTICLES ASAPPREVSeparationsNEXT Bin Pan Mork Family Department of Chemical Engineering and Materials Science, University of Southern California, 925 Bloom Walk, Los Angeles, California 90089-1211, United States , Lanja R.
Monitoring Waterlogging Damage of Winter Wheat Based on HYDRUS-1D and WOFOST Coupled Model and Assimilated Soil Moisture Data of Remote Sensing
2. Research Area and Data 2.1. Research Area In the northern part of Anhui Province of China, Guzhen County is located between 33°10′ and 33°30′ N latitude and 117°02′ and 117°36′ E longitude. From east to west, it is about 47 km wide, and from north to south, it is about 51 km long. The overall area is approximately 1363 square kilometers. illustrates the geographical location of the study area. The study area is a significant winter wheat planting area.
Application of water-soluble conjugated polymers in intelligent measurement and control of food microbial fermentation process
1 Introduction Microbial fermentation is the foundation of bioengineering, modern biotechnology, and industrialization (AO et al., 2020; Gargalo et al., 2020). With the continuous development of fermentation technology, the demand for intelligent MAC technology is also increasing. However, the mechanism of biological fermentation process is complex and highly nonlinear, and changes over time (Villarreal-Soto et al., 2018).
Liquid Permeability Determination from Vacuum Imbibition in Tight/Shale Core Plugs
Liquid permeability is a key petrophysical parameter that quantifies the ability of a liquid to flow through porous rock/soil and can be used in determining the efficiency of many subsurface processes, including enhanced hydrocarbon recovery, groundwater transport, carbon dioxide geostorage, underground hydrogen storage, etc.
Transcriptomic and proteomic profiling of the anterior cingulate cortex in neuropathic pain model rats
Introduction Neuropathic pain (NP), affecting approximately 10% of the world’s population, is a common type of pathological pain resulting from a lesion or dysfunction in the somatosensory system (Finnerup et al., 2021). As a debilitating medical condition, NP takes a heavy toll on individual well-being and poses a huge challenge to both pain physicians and neurologists (Scholz et al., 2019).
Investigation of Fracturing Fluid Flowback in Hydraulically Fractured Formations Based on Microscopic Visualization Experiments
1. Introduction Shale gas, an unconventional natural gas with huge potential and low carbon emissions, is currently one of the key energy sources being developed and exploited around the world [1]. Nowadays, four countries—China, the United States, Argentina and Canada—have achieved commercial development of shale gas [2,3]. Apart from them, Australia, Mexico, South Africa, and the United Kingdom are also actively promoting it [4,5].
Hydrophobic nanoporous carbon scaffolds reveal the origin of polarity-dependent electrocapillary imbibition
Hydrophobic nanoporous carbon scaffolds reveal the origin of polarity-dependent electrocapillary imbibition† Bin Pan, ab Manila Ozhukil Valappil, c Richard Rateick, Jr,d Christopher R. Clarkson,e Xia Tong,c Chris Debuhr,e Amin Ghanizadehe and Viola I.
Wettability in the methane (CH4)–liquid–rock system is a key parameter which determines gas recovery and geo-storage efficiencies. However, there is a lack of an overview over this area; thus, we critically review this parameter from experimental and theoretical perspectives and discuss the impact of pressure and temperature conditions, fluid properties (salinity, ion type, and aqueous versus nonaqueous) as well as rock surface chemistry and roughness.
A hybrid level set model for image segmentation
Loading metrics Open Access Peer-reviewed Research Article Weiqin Chen, Changjiang Liu , Anup Basu, Bin Pan Weiqin Chen, Changjiang Liu, Anup Basu, Bin Pan Published: June 7, 2021 https://doi.org/10.1371/journal.pone.0251914 Figures Abstract Active contour models driven by local binary fitting energy can segment images with inhomogeneous intensity, while being prone to falling into a local minima. However, the segmentation result largely depends on the location of the initial contour.
Melatonin promotes Schwann cell proliferation and migration via the shh signalling pathway after peripheral nerve injury
RESEARCH REPORT Hu Feng Corresponding Author fenghuxz@163.com Department of Orthopedics, the Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu Province, China Correspondence Hu Feng, MD, and Kaijin Guo, PhD, Department of Orthopedics, the Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu Province, China. Email: fenghuxz@163.com (H. F.); guokaijinxz@yeah.net (K.
Synthesis and applications of methyleneaziridines
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Microtransplantation for Acute Myeloid Leukemia
Key Points Question Is microtransplantation of hematopoietic cells a safe and effective therapy for persons with acute myeloid leukemia or myelodysplastic syndrome?
Safety and efficacy of chimeric antigen receptor (CAR)-T-cell therapy in persons with advanced B-cell cancers and hepatitis B virus-infection
Abstract Chimeric antigen receptor (CAR)-T-cell is a safe and effective therapy of B-cell cancers but it is unknown if this is so in persons with prior hepatitis B virus (HBV) infection. We studied 70 subjects with advanced B-cell cancers receiving CAR-T-cell therapy, 12 of whom had chronic HBV-infection (HBsAg positive) and 29 with resolved HBV-infection (HBsAg negative and anti-HBc positive). Safety and efficacy were compared with 29 subjects without HBV-infection.
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