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Articles by Binbin Xia
Identification of biomarkers for non-invasive diagnosis and risk stratification in prostate cancer using NMR-based metabolomics and machine learning
Abstract The non-invasive diagnosis and risk stratification of prostate cancer (PCa) remain clinically challenging due to the limited specificity of prostate-specific antigen (PSA). In this retrospective study, we applied a comparative machine learning (ML) framework to rank and select biomarkers from serum 1H nuclear magnetic resonance (NMR)-based metabolomics, subsequently developing three sequential metabolite panels.
Characteristic of Immunotherapy Trials in Head and Neck Squamous Cell Carcinoma: 2013-2023
Conflicts of Interest The authors declare no conflicts of interest. Supporting Information Filename Description odi15251-sup-0001-TableS1.xlsxExcel 2007 spreadsheet , 11.1 KB Table S1. References , , , et al. 2024. “Global Cancer Statistics 2022: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries.” CA: A Cancer Journal for Clinicians 74, no. 3: 229–263. , , , et al. 2019.
The alternative splicing landscape of infarcted mouse heart identifies isoform level therapeutic targets - Scientific Data
Abstract Alternative splicing is an important process that contributes to highly diverse transcripts and protein products, which can affect the development of disease in various organisms. Cardiovascular disease (CVD) represents one of the greatest global threats to humans, particularly acute myocardial infarction (MI) and subsequent ischemic reperfusion (IR) injury, which involve complex transcriptomic changes in heart tissues associated with metabolic reshaping and immunological response.
Antimicrobial mechanism of in-situ plasma activated water treatment of pathogenic Escherichia coli and Staphylococcus aureus biofilms
Abstract Aims: This study investigated the efficacy and mechanisms of inactivation of against Escherichia coli UTI89 and Staphylococcus aureus NCTC8325 through an in-situ plasma-activated water (PAW) treatment. Methods and Results: PAW was prepared by discharging atmospheric pressure cold plasma beneath the surface of sterile distilled water. The study investigated the inactivation of biofilm cells and biofilm matrix. A complete killing of biofilm cells was achieved on both of E.
Transcriptional Signatures Associated with the Survival of Escherichia coli Biofilm During Treatment with Plasma-Activated Water
Abstract Biofilm formation on surfaces, tools and equipment can damage their quality and lead to high repair or replacement costs. Plasma-activated water (PAW), a new technology, has shown promise in killing biofilm and non-biofilm bacteria due to its mix of reactive oxygen and nitrogen species (RONS), and in particular superoxide. However, the specific genetic mechanisms behind PAWs effectiveness, especially against biofilms, are not yet fully understood.
A closed-loop catalytic nanoreactor system on a transistor
Published In Science Advances Volume 9 | Issue 38 September 2023 Article versions Submission history Received: 5 June 2023 Accepted: 17 August 2023 Permissions See the Reprints and Permissions page for information about permissions for this article. Acknowledgments We thank K. Chi from Fudan University for the valuable discussion.
Plasma Activated Water as a Pre-Treatment Strategy in the Context of Biofilm-Infected Chronic Wounds
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Clinical Efficacy and Safety Evaluation of Ulinastatin Combined with Octreotide in the Treatment of Patients with Severe Acute Pancreatitis
Q. Ding, Yuxia Yao1, Huibo Wu1, Binbin Xia and H. Cheng* Department of Pharmacy, Beijing Luhe Hospital Captial Medical Univeisity, No. 82, Xinhua South Road, Tongzhou District, Beijing, China 1Department of Digestive System, Beijing Luhe Hospital Captial Medical Univeisity, No. 82, Xinhua South Road, Tongzhou District, Beijing, China *Corresponding Author: H.
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