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Articles by Biotechnology Development
A machine learning approach to a nine-SNP immunogenetic score for prognostic stratification in cervical cancer
1Group of Mycoplasmas, Laboratory of Molecular Microbiology, Vaccinology, and Biotechnology Development, Pasteur Institute of Tunis, University of Tunis El-Manar, Tunis, Tunisia 2Laboratory of Mycology, Pathologies, and Biomarkers (LR16ES05), Faculty of Sciences of Tunis, University of Tunis El Manar, Tunis, Tunisia 3Faculty of Sciences; University of Tunis El-Manar, Tunis, Tunisia Background: While human papillomavirus (HPV) is the primary driver of cervical cancer (CC), host immune-related...
Electrical or magnetic nerve stimulation enhance the BoNT/A-mediated muscle paralysis - Journal of NeuroEngineering and Rehabilitation
Das TK, Park DM. Effect of treatment with botulinum toxin on spasticity. Postgrad Med J. 1989;65(762):208–10. Google Scholar Elston JS, Russell RW. Effect of treatment with botulinum toxin on neurogenic blepharospasm. Br Med J (Clin Res Ed). 1985;290(6485):1857–9. Google Scholar Hesse S, Lucke D, Malezic M, et al. Botulinum toxin treatment for lower limb extensor spasticity in chronic hemiparetic patients. J Neurol Neurosurg Psychiatry. 1994;57(11):1321–4. Google Scholar Atassi MZ, Oshima M.
Apolipoprotein E genotypes are associated with diabetic peripheral neuropathy in Lebanese adults with type 2 diabetes: a case-control study
1 Introduction Type 2 diabetes mellitus (T2DM) is a chronic disorder of glucose regulation characterized by insulin resistance and insulin deficiency, contributing significantly to global morbidity and mortality (1, 2). Affecting over 537 million adults worldwide, with a prevalence projected to rise to 783 million by 2045 (3), T2DM is associated with macrovascular and microvascular complications (4, 5).
A sweeping view of avian mycoplasmas biology drawn from comparative genomic analyses - BMC Genomics
With genome sizes varying from 0.58 to 2.2 Mbp, bacteria belonging to the Mollicutes class are among the smallest self-replicating microorganisms [15]. This is thought to be the result of an extensive genome reduction that they have undergone during their evolution [16, 17]. The genome size of the 40 avian mycoplasmas under consideration in this study fall within this range, with a median size of ~ 0.919 Mbp. The genomes of the four M.
MicroRNA let‐7 targets BmCDK1 to regulate cell proliferation and endomitosis of silk gland in the silkworm, Bombyx mori
Supporting Information Filename Description ins13302-sup-0001-SuppMat.xlsx9.4 KB Table S1 List of primers used in this study. ins13302-sup-0002-SuppMat.xlsx9.7 KB Table S2 Summary of sequencing data. ins13302-sup-0003-SuppMat.xlsx31.8 KB Table S3 The differentially expressed genes in the body and silk gland between the let-7-KD silkworm and control silkworm. ins13302-sup-0004-SuppMat.xlsx9.4 KB Table S4 List of nine let-7 candidate target genes. ins13302-sup-0005-SuppMat.tif2.1 MB Fig.
Genomic changes underpinning the emergence of a successful Mycobacterium tuberculosis Latin American and Mediterranean clonal complex
Naira Dekhil* and Helmi Mardassi* Unit of Typing and Genetics of Mycobacteria, Laboratory of Molecular Microbiology, Vaccinology, and Biotechnology Development, Institut Pasteur, Tunis, University of Tunis El Manar, Tunis, Tunisia Introduction: The Latin American and Mediterranean sublineage (L4.3/LAM) is the most common generalist sublineage of Mycobacterium tuberculosis lineage 4 (L4), yet certain L4.3/LAM genotypes appear to be confined to particular geographic regions.
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