Between January 1, 2019, and June 30, 2020, 144 neonates admitted to three hospitals in southwest China with severe hyperbilirubinemia and meeting the following inclusion criteria were enrolled as the case group: (1) gestational age(GA) ≥ 35 weeks, within seven days of birth; (2) indirect bilirubin was the predominate component of serum bilirubin, accounting for more than 80% of the total bilirubin; (3) total bilirubin level met the exchange transfusion criteria in compliance with the...