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Articles by Blanca Sánchez-Ramírez
The role of carbonic anhydrases IX and XII in hypoxia-driven tumor adaptation and chemoresistance: an underexplored frontier for novel therapeutic strategies in ovarian cancer
Abstract Human carbonic anhydrases IX and XII (hCA IX/XII) regulate pH homeostasis and may facilitate tumor adaptation, progression, and therapeutic resistance. Although extensively studied in other malignancies, their roles in ovarian cancer (OC) remain insufficiently characterized. This narrative review critically examines their biological functions and therapeutic potential, emphasizing hypoxia and acidosis within the heterogeneous ovarian tumor microenvironment.
Computational Design and Synthesis of Phthalimide Derivatives as TGF-β Pathway Inhibitors for Cancer Therapeutics
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Folliculogenesis: A Cellular Crosstalk Mechanism
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Human TIMP1 Is a Growth Factor That Improves Oocyte Developmental Competence
1. Introduction Oocyte developmental competence refers to oocyte quality, defined as the oocyte’s ability to resume meiosis and complete its maturation. As a result, the oocyte is successfully fertilized and can support the transition to embryonic development. Competence is acquired during the growth of the oocyte in folliculogenesis, where it undergoes rearrangements at the nuclear and cytoplasmic levels [1].
Lactose recovery from Panela cheese whey: Effect of whey acidification on spontaneous and stirring‐induced crystallisation
Abstract This work aimed to investigate the kinetics, yield, size and composition changes in lactose crystals when Panela cheese whey was acidified (pH 3.80) or slightly alkalinised (pH 6.89) before being subjected to spontaneous or stirring-induced crystallisation. At pH 3.8, the crystallisation was accelerated, and the incorporation of salts and proteins in lactose crystals decreased. Nevertheless, these conditions induced the formation of amorphous lactose.
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