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Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. References , and . 2005. “Oxidative Stress, DNA Damage and Apoptosis in Male Infertility: A Clinical Approach.” BJU International 95: 503–507. https://doi.org/10.1111/J.1464-410X.2005.05328.X. , , , and . 1990.
Sulforaphene is a derivative of glucosinolate and a potential bioactive substance used for treating colon cancer. This study aimed to evaluate the potential inhibitory effect and mechanisms of sulforaphene in human colon cancer Caco-2 cells. Network pharmacology, molecular docking, and experimental verification were performed to elucidate potential sulforaphene mechanisms in the treatment of this condition.
Enrichment of the protein structural domain and KEGG pathway of DAPs Protein structural domains are specific components that recur in different protein molecules with similar sequence, structure, and function and are the units of protein evolution. Structural domains are usually between 25 and 500 amino acids in length. Of the results for the top 20 most significantly enriched classifications (Fig. 2(A)), all were downregulated for significantly different proteins.
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