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Articles by Boris Guiu
Effectiveness and safety of selective internal radiation therapy using yttrium-90 glass microspheres for hepatocellular carcinoma: real-world results from the multi-center prospective PROACTIF cohort of 989 patients
Keywords SIRT TARE Y90 HCC Real-world evidence Evidence before this study We searched PubMed for articles published in English between January 2000 and November 1, 2025, focusing on randomized studies in hepatocellular carcinoma (HCC), and using terms “selective internal radiation therapy” or “SIRT”, “radioembolization”, or “transarterial radioembolization” or “TARE”, “90Y” or “Y90”, AND “chemoembolization”, “sorafenib”, or “immunotherapy” for the comparator.
Long-Term Overall Survival After Selective Internal Radiation Therapy for Locally Advanced Hepatocellular Carcinomas: Updated Analysis of DOSISPHERE-01 Trial
hepatocellular carcinoma 90Y-loaded glass microspheres personalized dosimetry downstaged portal vein thrombosis Hepatocellular carcinoma is the most common primary liver cancer, being the third leading cause of cancer-related death worldwide, with approximately 745,000 deaths reported annually (1). Selective internal radiation therapy (SIRT) using 90Y-loaded glass microspheres can be used for patients with early-stage to locally advanced hepatocellular carcinoma (2,3).
Locoregional Treatment in Intrahepatic Cholangiocarcinoma: Which Treatment for Which Patient?
3. Which Treatment for Which Patient? The spectrum of liver-limited iCC varies greatly, and the applicability of the different LRTs differs, as their efficacy and safety profile differ between different situations.
Prolonged Survival after Recurrence in HCC Resected Patients Using Repeated Curative Therapies: Never Give Up!
Abstract : Simple Summary Surgical resection is the optimal treatment for hepatocellular carcinoma (HCC), despite a high risk of recurrence. We performed a retrospective analysis of survival after recurrence (SAR) of HCC after liver resection. Time to recurrence and treatment at recurrence are major prognostic factors of SAR. However, after curative treatment at recurrence, Overall survival is not significantly different between patients who recurred or not, whatever the time of recurrence.
Author Correction: Feasibility, safety and accuracy of a CT-guided robotic assistance for percutaneous needle placement in a swine liver model
Correction to: Scientific Reports https://doi.org/10.1038/s41598-021-84878-3, published online 04 March 2021 The original version of this Article contained an error in the order of the Figures. Figure 4 was published as Figure 7, Figure 6 was published as Figure 4, and Figure 7 was published as Figure 6. The Figure legends were correct. The original Figures 4, 6 and 7 and accompanying legends appear below. Figure 4 Screenshot of the planning software (home-made software).
Portal Vein Embolization versus 90Y Radioembolization:
This paper is only available as a PDF. To read, Please Download here. To read this article in full you will need to make a payment SIR Member Login Society Members, full access to the journal is a member benefit. Use your society credentials to access all journal content and features.
An In Vitro Evaluation of Four Types of Drug-Eluting Embolics Loaded with Idarubicin
Transarterial embolization is a widely accepted treatment for hepatocellular carcinoma (HCC) (1x1Llovet, J.M., Burroughs, A., and Bruix, J. Hepatocellular carcinoma. Lancet. 2003; 362: 1907–1917 Google ScholarSee all References, 2x2Yau, T., Tang, V.Y., Yao, T.J., Fan, S.T., Lo, C.M., and Poon, R.T. Development of Hong Kong Liver Cancer staging system with treatment stratification for patients with hepatocellular carcinoma. Gastroenterology. 2014; 146: 1691–1700 Google ScholarSee all References).
Efficacy of microwave ablation versus radiofrequency ablation for the treatment of hepatocellular carcinoma in patients with chronic liver disease: a randomised controlled phase 2 trial
Radiofrequency ablation is the recommended treatment for patients with hepatocellular carcinoma who have lesions smaller than 3 cm and are therefore not candidates for surgery. Microwave ablation is a more recent technique with certain theoretical advantages that have not yet been confirmed clinically. We aimed to compare the efficacy of both techniques in the treatment of hepatocellular carcinoma lesions of 4 cm or smaller.
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