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Articles by Boyi Chen
In vivo-compatible spatial multi-omics via hydrogen peroxide-independent APEX2 labeling
Abstract Proximity labeling (PL) technologies such as APEX2 have transformed spatial multi-omics in live cells, but their long-standing dependence on hydrogen peroxide (H2O2) disrupts redox signaling and prevents use in live animals. Here we introduce H2O2-independent APEX2 (Hi-APEX), which uses a clickable tetrazine-phenol (TP) probe, requiring no enzyme engineering. We show that APEX2 directly catalyzes TP labeling without H2O2 via a mechanism requiring the probe’s tetrazine group and oxygen.
Three peaks metamaterial broadband absorbing materials based on ZnSe-Cr-InAs stacked disks arrays
Three peaks metamaterial broadband absorbing materials based on ZnSe-Cr-InAs stacked disks arrays Metamaterial absorbers show great potential in many scientific and technological applications by virtue of their sub-wavelength structure and easy to adjust the structure, and an important standard to measure the performance of absorbers is bandwidth.
Rapid Parametric Modeling and Robust Analysis for the Hypersonic Ascent Based on Gap Metrics
Abstract : This paper investigates a rapid modeling method and robust analysis of hypersonic vehicles using multidisciplinary integrated techniques. First, the geometrical configuration is described using parametric methods based on the class–shape technique. Aerodynamic forces and moments are estimated for the specific configuration using engineering methods.
Ultrasensitive dual enhanced electrochemical immunosensor to detect ancient wool relics
Ultrasensitive dual enhanced electrochemical immunosensor to detect ancient wool relics† Boyi Chen,a Zhongyuan Wang,a Junsen Wang,a Hailing Zheng, b Junyi Zhou,a Xushi Chen,a Bing Wang, *a Yang Zhou*b and Zhiqin Penga Author affiliations * Corresponding authors a School of Materials Science & Engineering, Zhejiang Sci-Tech University, Hangzhou 310018, China E-mail: wbing388@163.com Fax: +86-571-86843867 Tel: +86-571-86843867 b Key Scientific Research Base of Textile Conservation, State...
Ultrasensitive dual enhanced electrochemical immunosensor to detect ancient wool relics
Ultrasensitive dual enhanced electrochemical immunosensor to detect ancient wool relics Boyi Chen, Zhongyuan Wang, Junsen Wang, Hailing Zheng, Junyi Zhou, Xushi Chen, Bing Wang, Yang Zhou and Zhiqin Peng Abstract The identification of ancient wool is of great significance in archaeology; however, conventional methods are unwieldy or even ineffective when testing contaminated or severely degraded ancient samples.
Preparation of artificial antibodies and development of an antibody-based indirect ELISA for the detection of ancient wool
The use of wool from sheep is widespread in ancient and historic textiles. The detection of ancient wool can provide meaningful information for both archaeologists and academics. However, the efficacy of conventional methods is likely to be limited in the detection of ancient samples with severe degradation or contamination. This is also one of the main challenges in archaeological sites. In this study, a novel immunological approach was proposed to attack the difficulty.
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