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Articles by Brian Halliday
In silico trials for sex-specific patient inclusion criteria in cardiac resynchronization therapy
Abstract Cardiac resynchronization therapy (CRT) guidelines are based on clinical trials with limited female representation and inconsistent left bundle branch block (LBBB) definitions. Conventional QRS duration (QRSd) criteria show variable diagnostic accuracy between sexes, partly due to differences in heart size and remodelling.
Improving arrhythmic risk prediction using cardiac magnetic resonance within deep learning in ischemic heart disease
Abstract Sudden arrhythmic death remains a major clinical risk in ischemic heart disease (IHD), underscoring the need for improved risk stratification. Late gadolinium enhancement cardiac magnetic resonance (LGE-CMR) provides measures of scar burden and heterogeneity, but its incremental prognostic value beyond conventional markers such as left ventricular ejection fraction remains uncertain.
The Trump Gold Card And Proposed Trump Platinum Card: Legal, Practical, Tax, And Economic Considerations For High-Net-Worth Immigrants
Gs Green and Spiegel More Green and Spiegel is one of the world's oldest immigration law firms, with over 60 years of experience assisting a global clientele. Focusing exclusively on immigration law, the lawyers at Green and Spiegel provide a broad range of immigration services to individual, institutional, and corporate clients in Canada, the United States, and Europe. The Trump Gold Card immigration program has now been formally launched and is accepting applicants.
Navigating The Impacts Of A Government Shutdown On Immigration
As Congress was unable to come to an agreement regarding the Fiscal Year 2026 budget, the government has officially "shutdown" as many of its departments and offices do not have funding to continue operations and pay its employees. However, many departments, including those related to immigration, are either considered "essential" or "self-funded" and will continue operations in at least some capacity during the shutdown.
What Is The U.S. Immigration "Gold Card" Program?
On February 25, 2025, the Trump Administration floated the notion of a new investment-based avenue to U.S. permanent resident (green card) status called the "Gold Card" to replace the existing EB-5 Immigrant Investor Program. The EB-5 program, in existence for 25 years, has been criticized for being complicated, inefficient and susceptible to fraud.
The global landscape of peripartum cardiomyopathy: morbidity, mortality, recovery and inequity
Corresponding Author Maddalena Ardissino British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK National Heart and Lung Institute, Imperial College London, London, UK Medical Research Council Laboratory of Medical Sciences, Imperial College London, London, UK Department of Women and Children's Health, King's College London, London, UK Corresponding author.
State of the art: multimodality imaging in dilated cardiomyopathy
http://orcid.org/0000-0002-5876-1748Brian P Halliday1,2 1 CMR Unit and Inherited Cardiac Conditions Care Group, Royal Brompton and Harefield Hospitals, London, UK 2 National Heart and Lung Institute, Imperial College London, London, UK Correspondence to Dr Brian P Halliday, CMR Unit and Inherited Cardiac Conditions Care Group, Royal Brompton and Harefield Hospitals, London, London, UK; b.halliday{at}rbht.nhs.uk Abstract Dilated cardiomyopathy represents a common phenotype expressed in...
State of the art: multimodality imaging in dilated cardiomyopathy
http://orcid.org/0000-0002-5876-1748Brian P Halliday1,2 1CMR Unit and Inherited Cardiac Conditions Care Group, Royal Brompton and Harefield Hospitals, London, UK 2National Heart and Lung Institute, Imperial College London, London, UK Correspondence to Dr Brian P Halliday, CMR Unit and Inherited Cardiac Conditions Care Group, Royal Brompton and Harefield Hospitals, London, London, UK; b.halliday{at}rbht.nhs.uk Abstract Dilated cardiomyopathy represents a common phenotype expressed in...
Maintaining Success for Patients With Dilated Cardiomyopathy and Remission of Heart Failure:
JACC Journals › JACC: BTS › Archives › Vol. 7 No. 5 Summary Remission of heart failure, defined by resolution of symptoms, normalization of left ventricular ejection fraction, and plasma concentrations of natriuretic peptides and by the ability to withdraw diuretic agents without recurrence of congestion is increasingly recognized among patients with dilated cardiomyopathy. Once remission has been achieved, it is unclear which treatments need to be continued long term.
Prognostic Significance of Nonischemic Myocardial Fibrosis in Patients With Normal LV Volumes and Ejection-Fraction:
Abstract Objectives This study aims to investigate the prognostic significance of late gadolinium enhancement (LGE) in patients without coronary artery disease and with normal range left ventricular (LV) volumes and ejection fraction. Background Nonischemic patterns of LGE with normal LV volumes and ejection fraction are increasingly detected on cardiovascular magnetic resonance, but their prognostic significance, and consequently management, is uncertain.
Peripartum cardiomyopathy and pre‐eclampsia – two tips of the same iceberg
Editorial Comment Brian P Halliday PhD MRCP, Corresponding Author b.halliday@imperial.ac.uk National Heart and Lung Institute, Imperial College, London Cardiovascular Research Centre, Inherited Cardiovascular Conditions Care Group and CMR Unit, Royal Brompton Hospital Corresponding author.
Late-Gadolinium Enhancement Interface Area and Electrophysiological Simulations Predict Arrhythmic Events in Patients With Nonischemic Dilated Cardiomyopathy | JACC: Clinical Electrophysiology
Abstract Objectives This study sought to investigate whether shape-based late gadolinium enhancement (LGE) metrics and simulations of re-entrant electrical activity are associated with arrhythmic events in patients with nonischemic dilated cardiomyopathy (NIDCM). Background The presence of LGE predicts life-threatening ventricular arrhythmias in NIDCM; however, risk stratification remains imprecise.
Myocardial remodelling after withdrawing therapy for heart failure in patients with recovered dilated cardiomyopathy: insights from TRED‐HF
Abstract Aims To characterize adverse ventricular remodelling after withdrawing therapy in recovered dilated cardiomyopathy (DCM). Methods and results TRED‐HF was a randomized controlled trial with a follow‐on single‐arm cross‐over phase that examined the safety and feasibility of therapy withdrawal in patients with recovered DCM over 6 months.
Withdrawal of pharmacological treatment for heart failure in patients with recovered dilated cardiomyopathy (TRED-HF): an open-label, pilot, randomised trial
Brian P Halliday, PhD,a,b Rebecca Wassall, MSc,a Amrit S Lota, BMBCh,a,b Zohya Khalique, MBBS,a,b John Gregson, PhD,d Simon Newsome, MSc,d Robert Jackson, MSc,a Tsveta Rahneva, BSc,a Rick Wage, DCR,a Gillian Smith, PhD,a Lucia Venneri, MD,a Upasana Tayal, PhD,a,b Dominique Auger, MD,a William Midwinter, BSc,a,b Nicola Whiffin, PhD,a,b,c Ronak Rajani, MD,e Jason N Dungu, PhD,f Antonis Pantazis, MD,a Stuart A Cook, Prof, PhD,a,b,c,g James S Ware, PhD,a,b,c A John Baksi, PhD,a,b Dudley J...
Outcome in Dilated Cardiomyopathy Related to the Extent, Location, and Pattern of Late Gadolinium Enhancement
JACC: Cardiovascular Imaging Original Research Brian P. Halliday, A. John Baksi, Ankur Gulati, Aamir Ali, Simon Newsome, Cemil Izgi, Monika Arzanauskaite, Amrit Lota, Upasana Tayal, Vassilios S. Vassiliou, John Gregson, Francisco Alpendurada, Michael P. Frenneaux, Stuart A. Cook, John G.F. Cleland, Dudley J. Pennell and Sanjay K. Prasad Author + information vol. 12 no.
When can heart failure treatment be stopped safely? - Authors' reply
We thank Jennifer Thibodeau and Mark Drazner for their comments. As experienced clinicians, it is probable they have cared for patients with dilated cardiomyopathy who have made a full symptomatic recovery with apparent normalisation of cardiac function. Such patients frequently ask whether heart failure treatments can be stopped. What should we tell such patients? We do not think that anecdotes are the optimal basis for advising on treatment.
Withdrawal of pharmacological treatment for heart failure in patients with recovered dilated cardiomyopathy (TRED-HF): an open-label, pilot, randomised trial
Many patients deemed to have recovered from dilated cardiomyopathy will relapse following treatment withdrawal. Until robust predictors of relapse are defined, treatment should continue indefinitely. Between April 21, 2016, and Aug 22, 2017, 51 patients were enrolled. 25 were randomly assigned to the treatment withdrawal group and 26 to continue treatment.
Pence touts mining, raises money, during Duluth visit
Just a few weeks after President Trump came to Duluth to rally for Republican Eighth Congressonial District candidate Pete Stauber, Vice President Mike Pence followed on Wednesday to raise votes and money.Pence likely succeeded on the second front.
Red meat and reflected glory: In Duluth, Trump crowd gets exactly what it came for
It’s not easy being an outsider at a Trump rally.It’s not just the protesters, like the two at the rally in Duluth who were circled by Trump supporters chanting the president’s name until security hustled them out of Amsoil Arena. It’s anyone who questions the basic aspirations of Trump voters or the president himself.
Trump in Duluth: No 'humble-bragging' here
You’ve heard of “humble-bragging,” where you feign modesty while calling attention to how great you really are. Our president doesn’t mess around with such subtlety. He just flat-out brags. Also lies. And he came to Minnesota last night to remind us how great he is and how well everything has been going in America since he took over.I wasn’t in Duluth for the speech, but watched it on C-Span.
Amid glee over DFL 'disarray,' the Minnesota GOP will have to deal with its own discord
The first few days of June were a time of celebration for Minnesota Republicans.After Minnesota Attorney General Lori Swanson was not endorsed on the first ballot for reelection at the DFL State Convention on June 2, she withdrew her name from consideration and, days later, announced she would run for governor.Amid the chain reaction of candidate filings that followed — with Congressman Keith Ellison deciding to run for attorney general, which created an opening for his seat in the Fifth...
Sex‐ and age‐based differences in the natural history and outcome of dilated cardiomyopathy
We used proportional hazard modelling to examine the association between sex, age and all‐cause mortality in consecutive patients with DCM. Overall, 881 patients (290 women, median age 52 years) were followed for a median of 4.9 years. Women were more likely to present with heart failure (64.0% vs. 54.5%; P = 0.007) and had more severe symptoms (P < 0.0001) compared to men. Women had smaller left ventricular end‐diastolic volume (125 mL/m2 vs.
GOP endorses Housley, Newberger for U.S. Senate
The Minnesota Republican Party has had its share of charged, nail-biting moments at its state conventions. The first day of the 2018 convention in Duluth wasn’t one of them. After a long spell of downtime while convention organizers were forced to switch from faulty electronic ballots to paper balloting, the nearly 1,700 delegates endorsed state Sen. Karin Housley to run against DFL incumbent Tina Smith and state Rep. Jim Newberger to run against DFL incumbent Amy Klobuchar.
Johnson wins GOP endorsement, setting up primary against Pawlenty
The Minnesota Republican Party state convention in Duluth endorsed its former chair Jeff Johnson for governor Saturday, the same endorsement Johnson won eight years ago.Johnson’s deep roots in the party resulted in a third ballot victory by acclamation after challengers — Woodbury Mayor Mary Giuliani Stephens and former teacher Phillip Parrish — dropped out of balloting.
Why money - and miles - are so important in the 8th District DFL primary
In the four-way DFL primary to succeed Rep. Rick Nolan in Minnesota’s 8th Congressional District, it comes down to miles and money.Former state Rep. Joe Radinovich, Nolan’s former chief of staff, acknowledged as much as he kicked off a regional tour at Clyde Iron Works, a repurposed industrial crane factory in the heart of Duluth’s once-thriving west end.“I’m going to do this by wearing out my shoe leather, like I always have,” Radinovich told a group of about 40.
Amid Tea Party discontent, Emmer stands firm on his early record
U.S. Rep. Tom Emmer is facing a discharge of conservative discontent for the votes, alliances and choices he’s made in his first six months in office.
Outsiders, swamp drainers: How GOP candidates are positioning themselves for the governor's race
Keith Downey has been involved in Minnesota politics for nearly a decade, first as a state House representative and most recently as a two-term chairman of the Republican Party of Minnesota.But he’s running for governor of Minnesota in 2018 with a different message: He’s an outsider who will shake up state government. In campaign materials, Downey talks about his time as a business and information systems consultant who saw a “corrupt and broken” system in St. Paul.
Downey announces run for governor
Another Republican in the guv race. The Pioneer Press’ Rachel E. Stassen-Berger reports: “After four years of running the Minnesota Republican Party, former chairman Keith Downey is bidding to run the entire state. … Downey, who comes from a systems management background and has made a mark on the state by working on major changes in politics and government, took on leadership of the party in a time of political and financial turmoil.
Jeff Johnson announces run for governor
Johnson is giving it another shot. The Star Tribune’s J. Patrick Coolican reports: “Hennepin County Commissioner Jeff Johnson announced Wednesday he is running for governor in 2018. … Johnson, the 2014 Republican nominee, made his announcement with a polished video via social media, promising to restore “power, opportunity and freedom” to Minnesotans.
Obamacare-repeal vote: What’s at stake for Minnesota’s House Republicans
Today is the biggest day for congressional Republicans in years: this afternoon, the House of Representatives is expected to vote on the American Health Care Act, their chance — seven years in the making — to repeal the Affordable Care Act and replace it with a law of their own.Republicans have run — and won — on this promise every election cycle since 2010.
One month in, Minnesota Republicans have plenty to like (and a few concerns) about Trump's presidency
A random sampling of some longtime Minnesota Republicans shows that after one month, the honeymoon with President Donald Trump isn’t over yet — even it was an arranged marriage from the start.MinnPost photo by Brian HallidayMarty SeifertMarty Seifert, a former GOP legislator and minority leader, who like many GOP influencers supported Sen. Marco Rubio during the Republican primaries, observed: “Usually, early on administrations have a hiccup with personnel.
Better late than never? Opposing Trump, Democrats take lessons from Tea Party
Joy Stroup never really got involved in politics until Donald Trump was elected president.A homemaker and substitute teacher from Plymouth, Stroup felt disgusted and defeated when Trump’s Electoral College victory sent him to the White House. Galvanized by that feeling, she demonstrated at the Women’s March in St. Paul the day after inauguration, along with her 14-year old daughter and about 100,000 others.The experience left Stroup with energy and passion to spare, but no obvious outlet for it.
Trump's campaign always knew it could be competitive in Minnesota
Minnesota was always in play for Donald Trump. So says his state campaign director and other Trump activists, who maintain that Trump’s narrow loss to Hillary Clinton here is nothing short of a political realignment — and that the DFL and Republican Party of Minnesota had better pay attention.Trump’s campaign director in Minnesota was Andy Post, a 28-year old from Lakeville who says the Trump campaign recognized the opportunity the state presented shortly after the candidate’s nomination in July.
GOP victory party offers a first look at a new, and different, Minnesota Republican Party
If the face of the Minnesota Republican Party is going to change with the election of Donald Trump, some of those new faces were at the Radisson Blu celebrating Trump’s victory.Aside from the party officers, this was not the usual cadre of GOP activists, at least not the ones I’ve encountered at similar events over the years. They were young. There were faces of different colors.
'Never Trump' is toast in the Minnesota GOP. Can the party move on in one piece?
The effort to resist Donald Trump in Minnesota fell in a hail of nays on the floor of the state Republican convention in Duluth this past weekend — and it’s now probably done for good.On Friday afternoon, a delegate at the state central committee meeting — where the truest of the party’s true believers convene — introduced a resolution, styled as a “party unity” measure.It said the Minnesota GOP would “continue to welcome all volunteers… Regardless of their level of support for any particular...
With Rubio out, here's what happens to the delegates he won in Minnesota
Editor’s note: this post has been updated to add information and clarify the column.Sen.
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