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Articles by Brigham Young
Novel Protein Purification Strategies and Structural Insights Into Vacuolar Protein Sorting 34 Inhibitor Binding for Structure-Guided Drug Discovery
Computational, Mathematical, and Physical Sciences; Chemistry and Biochemistry https://lib.byu.edu/about/copyright/ Abiodun, Wisdom Oshireku, "Novel Protein Purification Strategies and Structural Insights Into Vacuolar Protein Sorting 34 Inhibitor Binding for Structure-Guided Drug Discovery" (2026). Theses and Dissertations. 11468.
Simulation data for "Dendro-GR at high mass ratios with high spins"
Raw output of the eight Dendro-GR binary-black-hole simulations analysed in "Dendro-GR at high mass ratios with high spins" (Black, Neilsen, Hirschmann, & Van Komen 2026, arXiv:2607.26359).
Reporting framework for event-based model diagnostics
Abstract Event-Based Models (EBMs) are widely used to infer latent disease progression from cross-sectional biomarker data, with existing studies employing diverse approaches to characterize uncertainty, stability, and validation. However, comparatively little guidance exists for systematically integrating and reporting these complementary forms of diagnostic evidence.
PyMFCAD: v0.5.1
PyMFCAD is a Python package for rapid design and prototyping of 3D-printed microfluidic devices. It provides a component-based workflow for building reusable parts, assembling devices, routing connections, visualizing results, and generating printer-ready slices. Version Information: 0.5.0 -> 0.5.1 (2026-10-30) Minor documentation and developer bugs fixed. Fixed error in installation instructions Clarified visualizer menus Fixed bugs in make release See 0.5.0
Motor control of song and song-like vocalizations in the white-crowned sparrow
The sound production mechanisms described here for the white-crowned sparrow add to our knowledge of the various ways the two syringeal sound sources are used for generating acoustically and temporally complex vocal features. The data illustrate how the use of two sound generators for song production differs in white-crowned sparrows from that of other species.
HESS Opinion: Beyond the Machine Learning Paradox in Hydrology: A Framework for Scientifically Useful Modeling
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Reliability and criterion validity of abductor hallucis muscle volume measurements using ultrasound and MRI by assessors with limited image analysis experience
Loading metrics Open Access Peer-reviewed Research Article Citation: Willes JB, Robinson E, Sponbeck JK, Swanson DA, Swanson DC, Goodrich AG, et al. (2026) Reliability and criterion validity of abductor hallucis muscle volume measurements using ultrasound and MRI by assessors with limited image analysis experience. PLoS One 21(10): e0360725. https://doi.org/10.1371/journal.pone.0360725 Editor: Jeremy P.
Diurnal cortisol, perceived sleep quality, actigraphic sleep and depression: an exploratory pilot in patients with head and neck cancer
Abstract Background: In patients with head and neck cancer (HNC), perceived sleep quality, actigraphy-derived sleep parameters, depressive symptoms, and diurnal cortisol may represent related behavioral and biological processes. This exploratory study tested a priori associations among these constructs.
Shared sleep fragmentation in undergraduate roommates: dyadic actigraphy in a dense urban campus setting
Abstract Introduction: Dyadic sleep research has focused on romantic partners, leaving open whether nonromantic people who share a sleep space show related sleep. We examined sleep continuity and roommate concordance among undergraduate roommate dyads on a dense urban campus bordered by an interstate highway, freight-rail corridors, and an overnight air-cargo hub. The setting is described as context; no environmental exposure was measured.
Association between cardiovascular disease risk and cognitive function in older adults based on the China-PAR model: a cross-sectional study
Abstract Objective: To investigate the association between cardiovascular disease (CVD) risk and cognitive function in older adults using the China-PAR model. Methods: This study adopted stratified random sampling. A total of 570 older adults were selected from 3,750 health examinations at a community health service station, with sample size calculated by the cross-sectional study formula.
Sex Predators Use Dating Apps as Hunting Grounds
Author: Brigham Young University Author Contact: Sexual Diversity Published: 18th Nov 2022 - Updated: 23rd Mar 2026 Peer-Reviewed Publication: Yes Additional References: LGBTQ+ Dating Publications Summary: Study reveals dating apps are fertile ground for predators in part because there are few means for potential victims to screen possible partners.
Integration of a Structural Coherence Model with a Semi-Universal Machine Learning Interatomic Potential to Predict Molten Salt Thermal Conductivity
K. Vignarooban, X. Xu, A. Arvay, K. Hsu, A.M. Kannan, Heat transfer fluids for concentrating solar power systems—a review. Appl. Energy 146, 383–396 (2015). https://doi.org/10.1016/j.apenergy.2015.01.125https://www.sciencedirect.com/science/article/pii/S0306261915001634 Article ADS Google Scholar J.A. Wilson, M. Aziziha, J. Schorne-Pinto, A. Padinhare Manissery, J. Paz Soldan Palma, C.M. Dixon, R.E. Booth, H.B. Tisdale, Y. Zhoujin, D.S. Maltsev, S. Dai, P.W. Halstenberg, S. Huang, R. Jin, H.-C.
The complete defensive strategy: Defining complementary pitching and fielder positioning strategies in baseball
Citation: Melville W, Archibald C, Grimsman D (2026) The complete defensive strategy: Defining complementary pitching and fielder positioning strategies in baseball. PLoS One 21(10): e0341045. https://doi.org/10.1371/journal.pone.0341045 Editor: Cigdem Kadaifci, Istanbul Technical University: Istanbul Teknik Universitesi, TÜRKIYE Received: December 29, 2025; Accepted: August 22, 2026; Published: October 7, 2026 Copyright: © 2026 Melville et al.
Editorial: Spatial aspects of urban animal ecology and conservation biology, volume II
Volume I: Spatial Aspects of Urban Animal Ecology and Conservation biology framed urban animal ecology around broad spatial questions including habitat fragmentations, habitat and resource use, green spaces and corridors, comparisons between urban and less urbanized environments, and the use of landscape ecology metrics to inform conservation policy. Volume II continues many of these themes but does so by including more applied case studies.
β-Hydroxybutyrate Maintains Energetically Demanding Neural Functions During Exogenous Glucose Deprivation
Animal Care and Ethical Approval All animal procedures were approved by the Institutional Animal Care and Use Committee (IACUC) and conducted in accordance with institutional guidelines. Experiments were performed using male and female C57BL/6 mice aged 3–9 weeks. Animals were housed in individually ventilated cages under a 12-hour light/dark cycle with ad libitum access to food (LabDiet 5001) and hyperchlorinated reverse osmosis-filtered water.
The Qβ bacteriophage nanoparticle contributes to the adjuvanticity of antiglycan vaccines through a unique inflammatory pathway
adjuvant, innate sensing, vaccine, virus-like particle Introduction Vaccination continues to be an important tool in global health and essential in control against an expanding world of new pathogens.1 While some heat-killed pathogens or attenuated live strains create enough recognition and inflammation to trigger an immune response, many subunit, conjugate, and messenger RNA (mRNA) vaccines require additional adjuvants in order to trigger recognition by the immune system.2 Although there is...
High-throughput label-free single-cell proteomics enabled by multicolumn NanoLC
Competing interests T.T., X.X., and R.T.K. have a financial interest in MicrOmics Technologies, which provided LC columns for this work. The remaining authors declare no competing interests. Artificial intelligence use statement Artificial intelligence tools, including OpenAI ChatGPT (GPT-5.5), were used to assist with manuscript editing, code generation, and preliminary organization of Gene Ontology (GO) terms into broader biological themes.
In search of vitamin sleep: cross-sectional analysis of vitamin and mineral intake and sleep health outcomes in adolescents
Abstract Objectives: Many U.S. youth fail to meet nutritional guidelines and often struggle with inadequate sleep. We examined how adolescent micronutrient intake is related to sleep. We hypothesized that higher intake of folic acid, potassium, calcium, magnesium, vitamin D, vitamin K, and iron would be associated with earlier chronotype, reduced daytime sleepiness, earlier DLMO timing, and less circadian misalignment.
Evaluating online family life education modules across family stages: a pilot study
Abstract Objective: To evaluate whether online family life education (FLE) modules improved knowledge, attitudes, and confidence about key family health topics among young, middle, and older adults. Background: Family life education supports healthy familial relationships across generations. Traditionally, FLE has been offered in-person over multiple weeks. Online FLE could make it easier to reach families.
Filtered Mapped NCIT Ontology Terms for AnnotatedBCGEData
Published September 17, 2026 | Version v5 These are the files that AnnotatedBCGEData pulls when searching datasets, called by the searchForDatasets function. This removed the comments column, added a code column, and read the data into a tsv. Newest version changed format, split lines based on values. Includes one line per field and value. Name Size md5:a27374bb4fe62bd5e5796e023358e030 278.3 kB
PyMFCAD: v0.5.0
Published September 3, 2026 | Version v0.5.0 PyMFCAD is a Python package for rapid design and prototyping of 3D-printed microfluidic devices. It provides a component-based workflow for building reusable parts, assembling devices, routing connections, visualizing results, and generating printer-ready slices. Version Information: 0.4.2 -> 0.5.0 (2026-09-03) Replaced slicer/print file generation with new workflow utilizing Workspaces. For more details see slicing section of documentation.
Synthetic Strategies for Bioactive Peptides: From Aggregation Inhibitors to the Total Synthesis of Tunicyclin C
Computational, Mathematical, and Physical Sciences; Chemistry and Biochemistry https://lib.byu.edu/about/copyright/ Garcia Morin, Stephanie Graciela, "Synthetic Strategies for Bioactive Peptides: From Aggregation Inhibitors to the Total Synthesis of Tunicyclin C" (2026). Theses and Dissertations. 11396.
Is “No Change” Really No Change?: A Qualitative Analysis of Clients With “No Change” on Routine Outcome Monitoring Who Report Improving in Therapy
Family, Home, and Social Sciences; Psychology https://lib.byu.edu/about/copyright/ Stewart Parker, Audrey Louise, "Is “No Change” Really No Change?: A Qualitative Analysis of Clients With “No Change” on Routine Outcome Monitoring Who Report Improving in Therapy" (2026). Theses and Dissertations. 11405. https://scholarsarchive.byu.edu/etd/11405 Dissertation routine outcome monitoring, paradoxical outcome, client perspective, psychotherapy, OQ-45
Discursive Consciousness and Pedagogical Reasoning Within Teacher Collaborative Inquiry in Rural Mexico
David O. McKay School of Education; Teacher Education https://lib.byu.edu/about/copyright/ Charles Martinez, Nelly Yllen, "Discursive Consciousness and Pedagogical Reasoning Within Teacher Collaborative Inquiry in Rural Mexico" (2026). Theses and Dissertations. 11437. https://scholarsarchive.byu.edu/etd/11437 teacher collaboration, teacher development, discursive consciousness, structure agency theory, pedagogically productive talk, pedagogical reasoning
Discoverability and characteristics of health and fitness apps for deaf/hard-of-hearing and blind/low-vision users
Abstract Purpose: Regular physical activity improves health, yet Deaf/hard-of-hearing (DHH) and blind/low-vision (BLV) individuals face persistent barriers to participation. Accessible fitness apps could improve health equity if they are discoverable in mainstream marketplaces and include meaningful accessibility features that support participation. Materials and methods: A scoping search of the Apple App Store was conducted using nine DHH/BLV-related terms.
Dataset DOI Spreadsheet
Published August 17, 2026 | Version v1 Name Size md5:3e0a6f5983139164d42136b4210907bf 141 Bytes
Scientists Say This Simple Habit Could Lead to a Happier Marriage
Couples who exercise together may gain more than physical benefits. Credit: Shutterstock A simple walk together could help couples communicate better, feel closer, and handle disagreements more effectively. New research from Brigham Young University found that young married couples who were physically active together tended to report better communication, stronger conflict resolution, and less marital stress. The association was stronger for shared exercise than for working out alone.
A Virtual-Center Spherical Joint for Reconfigurable Truss Robot Systems
ORIGINAL RESEARCH article Volume 13 - 2026 | doi: 10.3389/frobt.2026.1968425 Reviewed by ORIGINAL RESEARCH article AR Adam Rose LH Larry Howell Brigham Young University, Provo, United States Article metrics View details Abstract This work introduces and models the Virtual-Center Serial Linkage Spherical Joint (VCSL), a modular spherical joint design for reconfigurable truss robots that facilitates large changes in shape while also allowing the robot to be reconfigured into different structures.
Reshaping Home: Chinese Immigrant Women’s Adaptation and Family Transformation Under Exclusion
Keywords Chinese immigrant women, Chinese exclusion and family transformation, gender roles and cultural preservation Abstract In 1941, Jew Law Ying arrived at the port of San Francisco with her infant daughter, Bak Heong, seeking admission to join her merchant husband, Yung Hin Sen, in the United States.
Better call mom: Schools still see mothers as the default parent to contact
The start of the school year brings a familiar list of responsibilities for parents: buying school supplies, keeping track of forms, coordinating transportation and responding to a steady stream of emails from teachers and administrators. Although many families strive to share these responsibilities, research has consistently found that mothers tend to shoulder a larger share of the work tied to their kids' schooling.
Better call mom: Schools still see mothers as the default parent to contact
The start of the school year brings a familiar list of responsibilities for parents: buying school supplies, keeping track of forms, coordinating transportation and responding to a steady stream of emails from teachers and administrators.
Loneliness and Cardiovascular Disease: Intersecting Health Challenges in Patient-Centred Care
Key words loneliness social isolation social disconnection cardiovascular disease social determinants of health Get full text access Log in, subscribe or purchase for full access. References 1. Leigh-Hunt, N. ∙ Bagguley, D. ∙ Bash, K. ... An overview of systematic reviews on the public health consequences of social isolation and loneliness Public Health. 2017 Nov; 152:157-171 2. Holt-Lunstad, J. ∙ Smith, T.B. ∙ Baker, M. ...
A scoping review and systems thinking synthesis of scale-up frameworks
Background There is a pressing need to scale-up health and human services. While there are many scale-up frameworks in the broader literature, most of the general scale-up frameworks treat scale-up as a linear process. There are calls to bolster research viewing scale-up as a dynamic process. The purpose of this review is to consolidate and apply systems thinking to existing scale-up frameworks to illustrate feedback relationships among the drivers of scale-up.
The lived experiences of reproductive-aged women with polycystic ovary syndrome: a qualitative study
Background PCOS is a complex health condition that affects up to 20% females of reproductive age worldwide, and approximately 5 million U.S. females of reproductive aged females. Despite the prevalence of the condition, research on the lived experiences of women with PCOS is limited, particularly in the United States. Methods This study employed a phenomenological qualitative design to explore the lived experiences of individuals diagnosed with PCOS.
Sweet apple e-cigarette vapor differentially modulates the mTOR pathway in oral squamous cell carcinoma cell lines
Abstract Objectives: Oral squamous cell carcinoma (OSCC) is the most common head and neck cancer and is associated with high recurrence and poor prognosis. This study investigated the effects of Sweet Apple e-cigarette vapor extract (Apple EVE), with and without nicotine, on mTOR pathway activation in OSCC cell lines Ca9–22 and Cal 27.
Recent advances and opportunities for multi-robot systems in oceanography
REVIEW article Front. Mar. Sci., 13 July 2026 Sec. Ocean Observation Volume 13 - 2026 | https://doi.org/10.3389/fmars.2026.1823155 Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Design, Manufacturing, and Engineering Design Validation of a Fetal Activity Monitor
Fetal movement monitoring is an important indicator of fetal health, but current methods often rely on subjective self-reporting or medical equipment that may not be universally available. The research described in this thesis describes the design, manufacture, and engineering validation of a wearable fetal activity monitor based on nanocomposite wide-range strain gauge technology.
Mechanical characterization of vertically aligned carbon nanotube forest microelectrodes for neural interfacing
Abstract Introduction: This study aims to explore the mechanical properties of porous microelectrodes formed from vertically aligned carbon nanotube (CNT) forests. Specifically, we investigate the range of effective CNT-based microelectrode (ME) moduli that can be fabricated and identify moduli within that range that significantly reduce strain on brain tissue during micromotion.
Practical Implementation of Ethnomathematics to Increase the Engagement, Math Self-Efficacy, and Hawaiian Cultural Identity of Hawaiʻi Algebra 2 Students
David O. McKay School of Education; Educational Inquiry, Measurement, and Evaluation https://lib.byu.edu/about/copyright/ Kaluhiokalani, Kamalani George Mamatuki, "Practical Implementation of Ethnomathematics to Increase the Engagement, Math Self-Efficacy, and Hawaiian Cultural Identity of Hawaiʻi Algebra 2 Students" (2026). Theses and Dissertations. 11307.
Effects of a Peer Mentoring Program for Adolescent Newcomers on Feelings of Peer Connectedness and School Belonging
David O. McKay School of Education; Counseling Psychology and Special Education https://lib.byu.edu/about/copyright/ Barnhill, Eden Elizabeth Moon, "Effects of a Peer Mentoring Program for Adolescent Newcomers on Feelings of Peer Connectedness and School Belonging" (2026). Theses and Dissertations. 11295. https://scholarsarchive.byu.edu/etd/11295 peer mentoring, refugee, immigrant, adolescent, belonging
Data Science in the Utah Draft K-12 Standards of Mathematics
Abstract In today's data-driven world, the field of data science is becoming increasingly important. Research has shown that more job listings in Utah require applicants to have data science skills than ever before. Due to this growing demand, there is a push to begin data science instruction in grades K-12; however, what data science instruction is in grades K-12 is not yet clearly defined.
Dual Language Immersion in Utah Schools: Examining Experiences and Access to Improve Sustainability
David O. McKay School of Education; Counseling Psychology and Special Education https://lib.byu.edu/about/copyright/ Kimball, Melissa Catherine Jensen, "Dual Language Immersion in Utah Schools: Examining Experiences and Access to Improve Sustainability" (2026). Theses and Dissertations. 11355. https://scholarsarchive.byu.edu/etd/11355 dual language immersion, foreign language, bilingual education
Removal of CD5 on T cells alters their differentiation and cytokine production in an in vitro model investigating effects of P. gingivalis LPS on oral epithelial and immune cells
Abstract Introduction: Periodontal disease is a highly prevalent oral inflammatory disease that affects nearly half of adults 30 years or older in the United States. It is characterized byexcessive inflammation within the periodontal pockets typically in response to bacterial challenge and is characterized by inflamed gums, destruction of periodontal ligaments, alveolar bone loss, and tooth loss if left untreated.
3D_printer_json_print_file
Description Add state machine diagram file. Notes If you use this software, please cite it as below.
Custom DLP-SLA 3D Printer Control System
Published June 5, 2026 | Version 1.0 Software Open A sophisticated control system for custom DLP-SLA 3D printers, built with Flask and WebSocket communication. This system provides a robust web interface for controlling and monitoring 3D printing operations, with support for various hardware configurations and real-time feedback. Name Size md5:687636ac2ac18de74dcf46a1c87b6342 25.7 MB https://github.com/3D-Printing-for-Microfluidics/3D_printer_control Python , JavaScript , HTML Active
Phosphorus Recycling in a Large Eutrophic Lake: The Magnitude of Internal Phosphorus Loads to Utah Lake, Utah (USA) Compared to External Sources
ORIGINAL RESEARCH article Volume 14 - 2026 | doi: 10.3389/fenvs.2026.1901468 Reviewed by ORIGINAL RESEARCH article SV Susana Velasquez-Franco 2 CS Charles S. Davidson 3 NJ Norman Jones 1 SN Stepehn Nelson 1,4 1. Brigham Young University, Provo, United States 2. Colombian Geological Survey, Bogota, Colombia 3. Natural History Museum of Utah, Salt Lake City, United States 4.
PyMFCAD
Published June 5, 2026 | Version 0.3.1 Software Open PyMFCAD is a Python package for rapid design and prototyping of 3D-printed microfluidic devices. It provides a component-based workflow for building reusable parts, assembling devices, routing connections, visualizing results, and generating printer-ready slices. Name Size md5:2df65ddf63513657b36a9486fa165dd5 54.7 MB md5:3a425916c2f97def6fa2dbc82763acaa 21.5 MB https://github.com/3D-Printing-for-Microfluidics/pymfcad Python , JavaScript Active
Beyond accommodation: institutional and policy drivers of healthcare equity for signing deaf adults
Background Deaf and hard-of-hearing individuals who use a signed language experience persistent inequities in healthcare access, communication, and outcomes. Although federal accessibility policies mandate effective communication, implementation remains inconsistent and signing Deaf patients continue to report barriers that compromise safety, autonomy, and trust.
Do Losing Candidates Harbor Illiberal Attitudes?
Anastasopoulos, Lefteris. 2016. Estimating the gender penalty in house of representative elections using a regression discontinuity design. Electoral Studies 43:150–157. Article Google Scholar Anderson, Christopher J., André Blais, Shaun Bowler, Todd Donovan, and Ola Listhaug. 2005. Losers’ consent: elections and democratic legitimacy. Oxford University Press. Ballotpedia. 2022. Contested State Legislative Primaries, 2022. https://ballotpedia.org/Contested_state_legislative_primaries,_2022.
Source files for some non-GEO breast-cancer gene-expression datasets
Published May 9, 2026 | Version v1 Dataset Open 1. Brigham Young University For some of the datasets that we process, the source files are either no longer available, are stored in a less-stable repository, or are relatively difficult to process. We have placed these in this repository. Please refer to the following archives for details about the sources, licensing, etc.
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