1 Introduction The human microbiota, which includes bacteria, bacterial viruses, archaea, and fungi, is housed in distinct niches of the human body (e.g., skin, oral cavity, intestine, lungs, female reproductive tract (FRT)), with the gut harboring the highest abundance of microbial communities and the female reproductive tract as the lowest.[1] Within each niche, the microbiota is unique or with minimal overlap, and represents a fingerprint of an individual, albeit the overall composition is...