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Welding fumes contain various metals. Past studies, however, mainly focused on Manganese (Mn)-related neurotoxicity. This study investigated welding-related mixed metal exposure effects on MRI metrics in the basal ganglia (BG) and their dose–response relationship. Subjects with (N = 23) and without (N = 24) a welding exposure history were examined. Metal exposure was estimated with an exposure history questionnaire and whole blood metal levels.
Welding fumes contain various metals. Past studies, however, mainly focused on Manganese (Mn)-related neurotoxicity. This study investigated welding-related mixed metal exposure effects on MRI metrics in the basal ganglia (BG) and their dose-response relationship. Subjects with (N = 23) and without (N = 24) a welding exposure history were examined. Metal exposure was estimated with exposure history questionnaire and whole blood metal levels.
INTRODUCTION: Chronic excessive welding exposure may be related to higher metal accumulation and structural differences in different subcortical structures. We examined how welding affected brain structures and their associations with metal exposure and neurobehavioral consequences. METHODS: Study includes 42 welders and 31 controls without a welding history.
Arsenic is a naturally occurring element that is widely found in ground water and agricultural products and is one of the most abundant elements in the earth’s crust. Chronic arsenic exposure in humans is associated with diseases such as skin, lung, and hepatic cancer [1–3] and the primary sources of human exposure include ingestion of inorganic arsenic from contaminated water [4], industrial waste, pesticides, and inadequate mine waste disposal [5–7].
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