1 Introduction The formation of ordered symmetric protein oligomers via self-assembly plays a key role in the evolution of complexity, and thus is a common biological event across all domains of life.1 Oligomeric quaternary protein structures, such as fibres, tubes, rings, and polyhedrons, arise from the symmetric arrangement of a small number of unique subunits according to geometric constraints, thus bypassing the requirement for large amounts of genomic material while maximising the...
