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Abstract Brain aging is a major risk factor for cerebrovascular and neurodegenerative diseases, yet continuous cell-type changes across the human lifespan remain incompletely defined. Here, we integrate 15 prefrontal cortex (PFC) snRNA-seq datasets from 158 neurologically healthy donors (19–101 years) to construct an atlas of 587,878 nuclei.
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.