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Carola Eugenia Eva

As seen in: British Pharmacological Society
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Articles by Carola Eugenia Eva

Radiprodil, a selective GluN2B negative allosteric modulator, rescues audiogenic seizures in mice carrying the GluN2A(N615S) mutation

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By Ilaria Bertocchi, Lorenzo Cifarelli, Alessandra Oberto, Carola Eugenia Eva
| British Pharmacological Society
AGS audiogenic seizures AGS-RA audiogenic seizures followed by respiratory arrest G guanine GoF gain of function M2 transmembrane domain 2 N asparagine P postnatal day P-loops phosphate-binding loops RA respiratory arrest S serine V vehicle WR wild running 1 INTRODUCTION The N-methyl-D-aspartate receptor (NMDAR) is a tetrameric ionotropic channel containing two copies of the essential subunit GluN1 and two accessory subunits from either the GluN2(A-D) or the GluN3(A-B) family of GRIN genes...
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