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We read with interest the Correspondence from John Harrison and colleagues. We agree with the need for caution in generalising study conclusions. Indeed, the conclusions in our Article1x1Shilyansky, C, Williams, LM, Gyurak, A, Harris, A, Usherwood, T, and Etkin, A. Effect of antidepressant treatment on cognitive impairments associated with depression: a randomised longitudinal study. Lancet Psychiatry. ; ( )http://dx.doi.org/10.1016/S2215-0366(16)00012-2.
Antidepressant treatment failure is a common problem worldwide. In this study, we assess whether or not an important aspect of depression, cognitive impairment, is untreated by antidepressants by studying the effect of acute antidepressant treatment on a range of cognitive domains.
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