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1. Introduction Click to copy section linkSection link copied! The Cell Painting (CP) assay is a high-content screening method that enables an unbiased and high-throughput evaluation of pharmacological similarity among compounds by comparing the drug-induced morphological changes on cells.
1. Introduction Click to copy section linkSection link copied! The Cell Painting (CP) assay is a high-content screening method that enables an unbiased and high-throughput evaluation of pharmacological similarity among compounds by comparing the drug-induced morphological changes on cells.
Abstract Morphological profiling has recently demonstrated remarkable potential for identifying the biologi-cal activities of small molecules. Alongside the fully supervised and self-supervised machine learn-ing methods recently proposed for bioactivity prediction from Cell Painting image data, we intro-duce here a semi-supervised contrastive (SemiSupCon) learning approach.
New Results Morphological Profiling Dataset of EU-OPENSCREEN Bioactive Compounds Over Multiple Imaging Sites and Cell Lines Christopher Wolff, Martin Neuenschwander, Carsten Joern Beese, Divya Sitani, Maria C. Ramos, Alzbeta Srovnalova, Maria Jose Varela, Pavel Polishchuk, Katholiki E.
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