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Abstract RTS,S, a WHO-recommended malaria vaccine, targets the circumsporozoite protein (CSP) on the Plasmodium falciparum sporozoite surface. Emerging data suggest off-target (non-CSP) antibody responses are associated with RTS,S-induced protection, but vaccine-derived responses are challenging to differentiate from boosting of naturally acquired immunity in endemic areas.
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.