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Abstract Objectives Increasing resistance to antimicrobials used for the treatment of Clostridioides difficile infections necessitates reproducible antimicrobial susceptibility testing. Current guidelines take a one-size-fits-all approach and/or offer limited guidance. We investigated how the choice of medium affects measured MIC values across two sites. Methods We determined MIC values for the antimicrobials fidaxomicin, metronidazole and vancomycin for a representative collection of European C.
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by Perezimor Etifa 1, César Rodríguez 2, Céline Harmanus 3, Ingrid M. J. G. Sanders 3, Igor A. Sidorov 3, Olufunmilayo A. Mohammed 4, Emily Savage 4, Andrew R. Timms 4, Jane Freeman 5,6, Wiep Klaas Smits 3,7, Mark H. Wilcox 5,6 and Simon D.
Different studies have suggested that the sand of public playgrounds could have a role in the transmission of infections, particularly in children. Furthermore, free access of pets and other animals to the playgrounds might increase such a risk. We studied the presence of Clostridium difficile in 20 pairs of sandboxes for children and dogs located in different playgrounds within the Madrid region (Spain). Clostridium difficile isolation was performed by enrichment and selective culture procedures.
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