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Articles by Cemal Orhan
Modulation of SIRT1/PPARγ pathways and tight junction proteins by nicotinamide riboside under chronic variable stress
Chronic stress disrupts homeostasis, leading to major health problems such as liver damage, intestinal barrier dysfunction, and impaired glucose metabolism. Although current treatments, including anxiolytics, sedatives, antidepressants, and beta blockers, are effective, their adverse effects emphasize the need for safer alternatives.
Magnesium-L-theanine complex protects against liver and intestinal damage caused by chronic variable stress
Accepted manuscript Magnesium-L-theanine complex protects against liver and intestinal damage caused by chronic variable stress Published online by Cambridge University Press: 26 November 2025 Kazim Sahin* Affiliation: Department of Animal Nutrition, Faculty of Veterinary Medicine, Firat University, 23119, Elazig, Türkiye Mehmet Yabas Affiliation: Department of Immunology, Faculty of Medicine, Malatya Turgut Ozal University, 44210, Malatya, Türkiye Cemal Orhan Affiliation: Department of...
The Effect of Water-Soluble Alpinia Galanga Extract on Sleep and the Activation of the GABAAergic/Serotonergic Pathway in Mice
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Impact of a Novel Valerian Extract on Sleep Quality, Relaxation, and GABA/Serotonin Receptor Activity in a Murine Model
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
A highly bioavailable curcumin formulation ameliorates inflammation cytokines and neurotrophic factors in mice with traumatic brain injury
REFERENCES , , & (2015). Interactions of oxidative stress and neurovascular inflammation in the pathogenesis of traumatic brain injury. Molecular Neurobiology, 51(3), 966–979. https://doi.org/10.1007/s12035-014-8752-3 , & (2013). Traumatic brain ınjury pathophysiology and treatments: Early, intermediate, and late phases post-injury. International Journal of Molecular Sciences, 15(1), 309–341. https://doi.org/10.3390/ijms15010309 , , & (2010).
Pharmaceuticals | Free Full-Text | Lutein/Zeaxanthin Isomers and Quercetagetin Combination Safeguards the Retina from Photo-Oxidative Damage by Modulating Neuroplasticity Markers and the Nrf2 Pathway
1. Introduction Over recent years, LED technology has become increasingly prevalent owing to its superior energy efficiency and the ability to produce high light levels while using less power. Despite these advantages, it is widely recognized that LED lights can trigger phototoxicity in the retina through oxidative stress. This stress predominantly affects photoreceptors and the retinal pigment epithelium (RPE), leading to retinal damage [].
Nicotinamide Riboside and Phycocyanin Oligopeptides Affect Stress Susceptibility in Chronic Corticosterone-Exposed Rats
2. Materials and Methods 2.1. Animals A total of 49 male Wistar albino rats (8 weeks old, 180 ± 20 g) were used, and animals were reared in polypropylene cages conditioned at a temperature of 22 ± 2 °C, with 55 ± 5% humidity and a 12/12 h light/dark cycle. A regular chow diet and water were provided ad libitum.
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