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Abstract Photothermal therapy (PTT) is a local treatment that uses photothermal conversion agents (PTAs) to absorb light and produce heat in tumor tissue. The direct result is tumor ablation. At the same time, heat-damaged tumor cells may undergo immunogenic cell death (ICD). This process is often accompanied by the release of damage-associated molecular patterns (DAMPs), followed by dendritic cell activation and antigen presentation.
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