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Articles by Chanhee Lee
Homozygous CHD8 mutation intensifies ASD phenotypes and attenuates sex differences
Abstract CHD8 is a chromatin remodeler implicated in autism spectrum disorders (ASD) and multiple neurodevelopmental disorders, yet heterozygous Chd8-mutant mouse lines often exhibit only mild ASD-related phenotypes, leaving its role unclear. Because a complete knockout of Chd8 causes embryonic lethality, we generated viable homozygous Chd8-mutant mice carrying the human CHD8-Asn2373LysfsX2 mutation using a hybrid (C57BL6/J × 129/Sv) genetic background.
GPR54 regulates non-small cell lung cancer development via dopa decarboxylase - Signal Transduction and Targeted Therapy
Abstract Non-small cell lung cancer (NSCLC), the most common type of lung cancer, is a leading cause of cancer death. G protein-coupled receptor 54 (GPR54) plays a role in cancer development by interacting with its endogenous ligand kisspeptin encoded by the KISS1 gene. However, the role of GPR54 in NSCLC development is not yet fully understood. Here, we demonstrate that GPR54 regulates NSCLC development via dopa decarboxylase (DDC).
Outside Front Cover: Complementary Multi‐Resonance Thermally Activated Delayed Fluorescence Design for Blue OLEDs Beyond the Concentration Limit
Corresponding Author Prof.
Lithiation Diagnostics by Measuring Electrochemodynamics in Solid-State Batteries
Solid-state batteries (SSBs) have emerged as a promising solution to overcome the limitations of conventional lithium-ion batteries, particularly in terms of energy density, safety, and longevity. (1−6) Advances in SSB development have largely been driven by the advent of high-performance solid electrolytes, including polymers, sulfides, oxides, halides, and hexacyanometallates.
[2505.09945] Personalizing Large Language Models using Retrieval Augmented Generation and Knowledge Graph
Work on one of the world's most important websites and make an impact on open science.
Enhancing Real-Time Kinematic Relative Positioning for Unmanned Aerial Vehicles
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Nitro-Enabled Atroposelective Dynamic Kinetic Resolution of 2-Arylindoles by Phase-Transfer Catalysis
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Considerations for feeding corn dried distillers' grains to livestock
Lowering feed costs without altering production can increase dairy producers’ profitability. Nutritionists or dairy producers may be looking for alternative feed sources to reduce feed expenses. Corn-dried distillers’ grains with solubles are widely available in the U.S. as a feed ingredient for livestock animals. Because corn-dried distillers’ grains contains high protein (30 to 40% crude protein of dry matter), it can be a good protein feed as a substitution for soybean meal.
Unveiling Interfacial Dynamics and Structural Degradation of Solid Electrolytes in a Seawater Battery System
Unveiling Interfacial Dynamics and Structural Degradation of Solid Electrolytes in a Seawater Battery System Understanding the interfacial reaction between a solid electrolyte and reactive species is of vital importance for the development of various battery systems. In particular, the interaction between the solid electrolyte, aqueous media, and dissolved gaseous phases at catalysts affects reaction kinetics and hybrid battery performance.
Feeding Fat-Reduced Corn-Distillers Grain with Solubles to Dairy Cows
Corn dried distillers grains with solubles (DG) is a common feed ingredient for lactating cows due to its high protein and fiber contents. Because of its lower price compared with soybean meal (SBM), inclusion of DG in a diet can lower feed costs. However, production responses to a DG diet can vary dependent upon its inclusion rate. Typical DG contains high fat (10 to 13% on a dry matter (DM) basis) and polyunsaturated fatty acids.
Feeding Fat-Reduced Corn-Distillers Grain with Solubles to Dairy Cows
Corn dried distillers grains with solubles (DG) is a common feed ingredient for lactating cows due to its high protein and fiber contents. Because of its lower price compared with soybean meal (SBM), inclusion of DG in a diet can lower feed costs. However, production responses to a DG diet can vary dependent upon its inclusion rate. Typical DG contains high fat (10 to 13% on a dry matter (DM) basis) and polyunsaturated fatty acids.
Pros, cons of feeding distiller grains - Farm and Dairy
In the past decades, an increase in ethanol production increased production and availability of corn dried distillers grains with solubles, DG. Because DG is high in protein and fiber, it has been used as a feed ingredient in dairy rations. Because of its low price, inclusion of DG in a diet — for example, replacing soybean meal — can lower feed costs. However, DG contains high fat (10-12 percent on a dry matter basis) and polyunsaturated fatty acids.
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