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Articles by Chaodong Wang
Organic Photoredox Catalytic Difluoroalkylation of Unactivated Olefins to Access Difluoro-Containing Tetrahydropyridazines
Organic Letters Cite this: Org. Lett. 2024, XXXX, XXX Click to copy citationCitation copied! Learn about these metrics Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days. Citations are the number of other articles citing this article, calculated by Crossref and updated daily.
Photoinduced EDA Complex‐initiated Synthesis of Fluoroalkylated Isoquinolinonediones
Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
High-depth whole-genome sequencing identifies structure variants, copy number variants and short tandem repeats associated with Parkinson’s disease - npj Parkinson's Disease
Abstract While numerous single nucleotide variants and small indels have been identified in Parkinson’s disease (PD), the contribution of structural variants (SVs), copy number variants (CNVs), and short tandem repeats (STRs) remains poorly understood. Here we investigated the association using the high-depth whole-genome sequencing data from 466 Chinese PD patients and 513 controls.
Sulfonamide-directed site-selective functionalization of unactivated C(sp3)−H enabled by photocatalytic sequential electron/proton transfer - Nature Communications
Abstract The generation of alkyl radical from C(sp3)−H substrates via hydrogen atom abstraction represents a desirable yet underexplored strategy in alkylation reaction since involving common concerns remain adequately unaddressed, such as the harsh reaction conditions, limited substrate scope, and the employment of noble metal- or photo-catalysts and stoichiometric oxidants.
PCDHA9 as a candidate gene for amyotrophic lateral sclerosis - Nature Communications
Abstract Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease. To identify additional genetic factors, we analyzed exome sequences in a large cohort of Chinese ALS patients and found a homozygous variant (p.L700P) in PCDHA9 in three unrelated patients. We generated Pcdhα9 mutant mice harboring either orthologous point mutation or deletion mutation.
Photocatalyst-free H2O-regulated and regiodivergent multicomponent hydrogenation/bifunctional sulfonylation of alkynes
Photocatalyst-free H2O-regulated and regiodivergent multicomponent hydrogenation/bifunctional sulfonylation of alkynes An efficient and mild multicomponent reaction (MCR) for the preparation of vinyl sulfone is reported, which is achieved by hydrogenation/difunctional sulfonylation of alkynyl ester with the corresponding N-allyl bromodifluoroacetamides, DABSO and H2O under visible light conditions without the need for any metal catalysts or additives.
Self-photocatalyzed regulable alkylation of 2H-benzothiazoles with diverse aliphatic C-H donors
Self-photocatalyzed regulable alkylation of 2H-benzothiazoles with diverse aliphatic C–H donors† Jiadi Zhou,‡a Chaodong Wang,‡b Lei Huang,b Can Luo,b Shilu Ye,b Ning Xu,b Yunsheng Zhu,b Li Liu,b Quanlei Ren,b Zhi Chen,b Shengjie Songb and Jianjun Li *ab Abstract Here, we report a mild and efficient method that combines self-photoredox catalysis and hydrogen atom transfer to achieve the alkylation of 2H-benzothiazoles with alcohols, ethers, lactams, amides and alkane, which features broad...
K2S2O8-catalyzed Highly Regioselective Amidoalkylation of Diverse N-Heteroaromatics on Water under Visible Light Irradiation
K2S2O8-catalyzed Highly Regioselective Amidoalkylation of Diverse N-Heteroaromatics on Water under Visible Light Irradiation The K2S2O8-catalyzed versatile C(sp2)-C(sp3) bond formation with N-heteroaromatics and γ-lactams/amides was developed. Quinoxalin-2(1H)-one, quinoline, isoquinoline, phthalazine, and benzothiazole reacted with γ-lactams/amides to give the corresponding C(sp2)-H amidoalkylation products in moderate to good yields with high regioselectivity.
Antigen-specific immune responses to influenza vaccine in utero
J Clin Invest. 2007 Jun 1; 117(6): 1637–1646. Deepa Rastogi,1 Chaodong Wang,2 Xia Mao,3 Cynthia Lendor,3 Paul B. Rothman,4 and Rachel L. Miller3 Deepa Rastogi 1Children’s Hospital at Montefiore, Albert Einstein College of Medicine, New York, New York, USA. 2Department of Neurology, Jiangxi Provincial People’s Hospital, Nanchang, People’s Republic of China.
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